Distinct sets of αβ TCRs confer similar recognition of tumor antigen NY-ESO-1(157–165) by interacting with its central Met/Trp residues

Naturally acquired immune responses against human cancers often include CD8(+) T cells specific for the cancer testis antigen NY-ESO-1. Here, we studied T cell receptor (TCR) primary structure and function of 605 HLA-A*0201/NY-ESO-1(157–165)-specific CD8 T cell clones derived from five melanoma pati...

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Detalhes bibliográficos
Main Authors: Derré, Laurent, Bruyninx, Marc, Baumgaertner, Petra, Ferber, Mathias, Schmid, Daphné, Leimgruber, Antoine, Zoete, Vincent, Romero, Pedro, Michielin, Olivier, Speiser, Daniel E., Rufer, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567484/
https://ncbi.nlm.nih.gov/pubmed/18809922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807954105
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