The Calcium/Calmodulin-Dependent Kinases II and IV as Therapeutic Targets in Neurodegenerative and Neuropsychiatric Disorders

by Sałaciak, Kinga, Koszałka, Aleksandra, Żmudzka, Elżbieta, Pytka, Karolina
Published in Int J Mol Sci (2021)

Metabolic and Cardiovascular Benefits and Risks of EMD386088—A 5-HT(6) Receptor Partial Agonist and Dopamine Transporter Inhibitor

by Kotańska, Magdalena, Śniecikowska, Joanna, Jastrzębska-Więsek, Magdalena, Kołaczkowski, Marcin, Pytka, Karolina
Published in Front Neurosci (2017)

HBK-14 and HBK-15 with antidepressant-like and/or memory-enhancing properties increase serotonin levels in the hippocampus after chronic treatment in mice

by Pytka, Karolina, Gawlik, Katarzyna, Pawlica-Gosiewska, Dorota, Witalis, Jadwiga, Waszkielewicz, Anna
Published in Metab Brain Dis (2016)

HBK-14 and HBK-15 Do Not Influence Blood Pressure, Lipid Profile, Glucose Level, or Liver Enzymes Activity after Chronic Treatment in Rats

by Pytka, Karolina, Głuch-Lutwin, Monika, Knutelska, Joanna, Jakubczyk, Magdalena, Waszkielewicz, Anna, Kotańska, Magdalena
Published in PLoS One (2016)

Single Administration of HBK-15—a Triple 5-HT(1A), 5-HT(7), and 5-HT(3) Receptor Antagonist—Reverses Depressive-Like Behaviors in Mouse Model of Depression Induced by Corticosteron...

by Pytka, Karolina, Głuch-Lutwin, Monika, Kotańska, Magdalena, Waszkielewicz, Anna, Kij, Agnieszka, Walczak, Maria
Published in Mol Neurobiol (2017)

The selective 5-HT(1A) receptor biased agonists, F15599 and F13714, show antidepressant-like properties after a single administration in the mouse model of unpredictable chronic mi...

by Głuch-Lutwin, Monika, Sałaciak, Kinga, Gawalska, Alicja, Jamrozik, Marek, Sniecikowska, Joanna, Newman-Tancredi, Adrian, Kołaczkowski, Marcin, Pytka, Karolina
Published in Psychopharmacology (Berl) (2021)

The antidepressant- and anxiolytic-like activities of new xanthone derivative with piperazine moiety in behavioral tests in mice

by Pytka, Karolina, Żmudzka, Elżbieta, Lustyk, Klaudia, Rapacz, Anna, Olczyk, Adrian, Gałuszka, Adam, Waszkielewicz, Anna, Marona, Henryk, Sapa, Jacek, Barbara, Filipek
Published in Indian J Pharmacol (2016)

A Comparison of the Anorectic Effect and Safety of the Alpha(2)-Adrenoceptor Ligands Guanfacine and Yohimbine in Rats with Diet-Induced Obesity

by Dudek, Magdalena, Knutelska, Joanna, Bednarski, Marek, Nowiński, Leszek, Zygmunt, Małgorzata, Mordyl, Barbara, Głuch-Lutwin, Monika, Kazek, Grzegorz, Sapa, Jacek, Pytka, Karolina
Published in PLoS One (2015)

H(3) histamine receptor antagonist pitolisant reverses some subchronic disturbances induced by olanzapine in mice

by Dudek, Magdalena, Kuder, Kamil, Kołaczkowski, Marcin, Olczyk, Adrian, Żmudzka, Elżbieta, Rak, Aleksandra, Bednarski, Marek, Pytka, Karolina, Sapa, Jacek, Kieć-Kononowicz, Katarzyna
Published in Metab Brain Dis (2016)

Design, synthesis and anticonvulsant-analgesic activity of new N-[(phenoxy)alkyl]- and N-[(phenoxy)ethoxyethyl]aminoalkanols

by Rapacz, Anna, Waszkielewicz, Anna M., Pańczyk, Katarzyna, Pytka, Karolina, Koczurkiewicz, Paulina, Piska, Kamil, Pękala, Elżbieta, Budziszewska, Bogusława, Starek-Świechowicz, Beata, Marona, Henryk
Published in Medchemcomm (2016)

Chemically Homogenous Compounds with Antagonistic Properties at All α(1)-Adrenoceptor Subtypes but not β(1)-Adrenoceptor Attenuate Adrenaline-Induced Arrhythmia in Rats

by Pytka, Karolina, Lustyk, Klaudia, Żmudzka, Elżbieta, Kotańska, Magdalena, Siwek, Agata, Zygmunt, Małgorzata, Dziedziczak, Agnieszka, Śniecikowska, Joanna, Olczyk, Adrian, Gałuszka, Adam, Śmieja, Jarosław, Waszkielewicz, Anna M., Marona, Henryk, Filipek, Barbara, Sapa, Jacek, Mogilski, Szczepan
Published in Front Pharmacol (2016)

Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT(1A) and 5-HT(7) Antagonists in Animal Models

by Pytka, Karolina, Partyka, Anna, Jastrzębska-Więsek, Magdalena, Siwek, Agata, Głuch-Lutwin, Monika, Mordyl, Barbara, Kazek, Grzegorz, Rapacz, Anna, Olczyk, Adrian, Gałuszka, Adam, Błachuta, Marian, Waszkielewicz, Anna, Marona, Henryk, Sapa, Jacek, Filipek, Barbara, Wesołowska, Anna
Published in PLoS One (2015)

HBK-17, a 5-HT(1A) Receptor Ligand With Anxiolytic-Like Activity, Preferentially Activates ß-Arrestin Signaling

by Pytka, Karolina, Głuch-Lutwin, Monika, Żmudzka, Elżbieta, Sałaciak, Kinga, Siwek, Agata, Niemczyk, Katarzyna, Walczak, Maria, Smolik, Magdalena, Olczyk, Adrian, Gałuszka, Adam, Śmieja, Jarosław, Filipek, Barbara, Sapa, Jacek, Kołaczkowski, Marcin, Pańczyk, Katarzyna, Waszkielewicz, Anna, Marona, Henryk
Published in Front Pharmacol (2018)

Discovery of Novel pERK1/2- or β-Arrestin-Preferring 5-HT(1A) Receptor-Biased Agonists: Diversified Therapeutic-like versus Side Effect Profile

by Sniecikowska, Joanna, Gluch-Lutwin, Monika, Bucki, Adam, Więckowska, Anna, Siwek, Agata, Jastrzebska-Wiesek, Magdalena, Partyka, Anna, Wilczyńska, Daria, Pytka, Karolina, Latacz, Gniewomir, Przejczowska-Pomierny, Katarzyna, Wyska, Elżbieta, Wesołowska, Anna, Pawłowski, Maciej, Newman-Tancredi, Adrian, Kolaczkowski, Marcin
Published in J Med Chem (2020)