Design, synthesis and anticonvulsant-analgesic activity of new N-[(phenoxy)alkyl]- and N-[(phenoxy)ethoxyethyl]aminoalkanols

New derivatives of N-[(phenoxy)alkyl]- and N-[(phenoxy)ethoxyethyl]aminoalkanols have been synthesized and evaluated for their anticonvulsant activity in maximal electroshock (MES), maximal electroshock seizure threshold (MEST), and pentylenetetrazol (PTZ) tests. Their neurotoxicity was evaluated vi...

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Dettagli Bibliografici
Pubblicato in:Medchemcomm
Autori principali: Rapacz, Anna, Waszkielewicz, Anna M., Pańczyk, Katarzyna, Pytka, Karolina, Koczurkiewicz, Paulina, Piska, Kamil, Pękala, Elżbieta, Budziszewska, Bogusława, Starek-Świechowicz, Beata, Marona, Henryk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2016
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072507/
https://ncbi.nlm.nih.gov/pubmed/30108708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00537c
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