Contribution of reactive oxygen species to the anticancer activity of aminoalkanol derivatives of xanthone

Reactive oxygen species (ROS) are critically involved in the action of anticancer agents. In this study, we investigated the role of ROS in the anticancer mechanism of new aminoalkanol derivatives of xanthone. Most xanthones used in the study displayed significant pro-oxidant effects similar to thos...

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Dades bibliogràfiques
Publicat a:Invest New Drugs
Autors principals: Sypniewski, Daniel, Szkaradek, Natalia, Loch, Tomasz, Waszkielewicz, Anna M., Gunia-Krzyżak, Agnieszka, Matczyńska, Daria, Sołtysik, Dagna, Marona, Henryk, Bednarek, Ilona
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2017
Matèries:
Preclinical Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948269/
https://ncbi.nlm.nih.gov/pubmed/29116476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-017-0537-x
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