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Contribution of reactive oxygen species to the anticancer activity of aminoalkanol derivatives of xanthone

Reactive oxygen species (ROS) are critically involved in the action of anticancer agents. In this study, we investigated the role of ROS in the anticancer mechanism of new aminoalkanol derivatives of xanthone. Most xanthones used in the study displayed significant pro-oxidant effects similar to thos...

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Detalhes bibliográficos
Publicado no:Invest New Drugs
Main Authors: Sypniewski, Daniel, Szkaradek, Natalia, Loch, Tomasz, Waszkielewicz, Anna M., Gunia-Krzyżak, Agnieszka, Matczyńska, Daria, Sołtysik, Dagna, Marona, Henryk, Bednarek, Ilona
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948269/
https://ncbi.nlm.nih.gov/pubmed/29116476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-017-0537-x
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