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Single Administration of HBK-15—a Triple 5-HT(1A), 5-HT(7), and 5-HT(3) Receptor Antagonist—Reverses Depressive-Like Behaviors in Mouse Model of Depression Induced by Corticosterone

Studies suggest that the blockade of 5-HT(1A), 5-HT(7), and 5-HT(3) receptor may increase the speed of antidepressant response. 1-[(2,6-Dimethylphenoxy)ethoxyethyl]-4-(2-methoxyphenyl)piperazine hydrochloride (HBK-14) and 1-[(2-chloro-6-methylphenoxy)ethoxyethyl]-4-(2-methoxyphenyl)piperazine hydroc...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Pytka, Karolina, Głuch-Lutwin, Monika, Kotańska, Magdalena, Waszkielewicz, Anna, Kij, Agnieszka, Walczak, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884906/
https://ncbi.nlm.nih.gov/pubmed/28550529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-017-0605-4
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