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Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione derivatives as 5-HT(1A) receptor partial agonists

Current antidepressant therapy has several disadvantages related to the properties of antidepressants. Considering their unfavourable features, the process of searching for new antidepressant drugs with better safety and tolerability requires consistent efforts and many complementary studies. Seroto...

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Publicado en:PLoS One
Main Authors: Partyka, Anna, Zagórska, Agnieszka, Kotańska, Magdalena, Walczak, Maria, Jastrzębska-Więsek, Magdalena, Knutelska, Joanna, Bednarski, Marek, Głuch-Lutwin, Monika, Mordyl, Barbara, Janiszewska, Paulina, Wesołowska, Anna
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413516/
https://ncbi.nlm.nih.gov/pubmed/32764777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237196
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