Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT(1A) and 5-HT(7) Antagonists in Animal Models

The aim of this study was to further characterize pharmacological properties of two phenylpiperazine derivatives: 1-{2-[2-(2,6-dimethlphenoxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazynine hydrochloride (HBK-14) and 2-[2-(2-chloro-6-methylphenoxy)ethoxy]ethyl-4-(2- methoxyphenyl)piperazynine dihydroc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pytka, Karolina, Partyka, Anna, Jastrzębska-Więsek, Magdalena, Siwek, Agata, Głuch-Lutwin, Monika, Mordyl, Barbara, Kazek, Grzegorz, Rapacz, Anna, Olczyk, Adrian, Gałuszka, Adam, Błachuta, Marian, Waszkielewicz, Anna, Marona, Henryk, Sapa, Jacek, Filipek, Barbara, Wesołowska, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640659/
https://ncbi.nlm.nih.gov/pubmed/26554929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142499
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