Biopharmaceutic Planning in Pediatric Drug Development

Por Purohit, Vivek S.
Publicado em 2012

Interaction of dicaproyl phosphatidylserine with recombinant factor VIII and its impact on immunogenicity

Por Purohit, Vivek S., Balasubramanian, Sathyamangalam V.
Publicado em 2006

Influence of Aggregation on Immunogenicity of Recombinant Human Factor VIII in Hemophilia A Mice

Por PUROHIT, VIVEK S., MIDDAUGH, C. RUSSELL, BALASUBRAMANIAN, SATHYAMANGALAM V.
Publicado em 2006

Intravenous administration of Factor VIII - O-Phospho-L-Serine (OPLS) complex reduces immunogenicity and preserves pharmacokinetics of the therapeutic protein

Por Gaitonde, Puneet, Purohit, Vivek S., Balu-Iyer, Sathy V.
Publicado no Eur J Pharm Sci (2014)

O-phospho-L-serine, multi-functional excipient for B domain deleted recombinant factor VIII

Por Miclea, Razvan D., Purohit, Vivek S., Balu-Iyer, Sathy V.
Publicado em 2007

Aggregation Kinetics of Recombinant Human FVIII (rFVIII)

Por RAMANI, KARTHIK, PUROHIT, VIVEK, MIDDAUGH, C. RUSSELL, BALASUBRAMANIAN, SATHYAMANGALAM V.
Publicado em 2005

Lower Inhibitor Development in Hemophilia A Mice following Administration of Recombinant Factor VIII-O-Phospho-l-serine Complex

Por Purohit, Vivek S., Ramani, Karthik, Sarkar, Rita, Kazazian, Haig H., Balasubramanian, Sathyamangalam V.
Publicado em 2005

Lipid Binding Region (2303–2332) Is Involved in Aggregation of Recombinant Human FVIII (rFVIII)

Por RAMANI, KARTHIK, PUROHIT, VIVEK S., MICLEA, RAZVAN D., MIDDAUGH, C. RUSSELL, BALASUBRAMANIAN, SATHYAMANGALAM V.
Publicado em 2005

Passive Transfer of Polyethylene glycol to Liposomal-Recombinant Human FVIII Enhances its Efficacy in a Murine Model for Hemophilia A

Por RAMANI, KARTHIK, PUROHIT, VIVEK, MICLEA, RAZVAN, GAITONDE, PUNEET, STRAUBINGER, ROBERT M., BALU-IYER, SATHY V.
Publicado em 2008

Phosphatidylserine Containing Liposomes Reduce Immunogenicity of Recombinant Human Factor VIII (rFVIII) in a Murine Model of Hemophilia A

Por RAMANI, KARTHIK, MICLEA, RAZVAN D., PUROHIT, VIVEK S., MAGER, DONALD E., STRAUBINGER, ROBERT M., BALU-IYER, SATHY V.
Publicado em 2008

Treatment of plaque psoriasis with an ointment formulation of the Janus kinase inhibitor, tofacitinib: a Phase 2b randomized clinical trial

Por Papp, Kim A., Bissonnette, Robert, Gooderham, Melinda, Feldman, Steven R., Iversen, Lars, Soung, Jennifer, Draelos, Zoe, Mamolo, Carla, Purohit, Vivek, Wang, Cunshan, Ports, William C.
Publicado no BMC Dermatol (2016)

IL-12 Delivered Intratumorally by Multilamellar Liposomes Reactivates Memory T Cells in Human Tumor Microenvironments

Por Simpson-Abelson, Michelle R., Purohit, Vivek S., Pang, Wing Man, Iyer, Vandana, Odunsi, Kunle, Demmy, Todd L, Yokota, Sandra J., Loyall, Jenni L., Kelleher, Raymond J., Balu-Iyer, Sathy, Bankert, Richard B.
Publicado em 2009

Summary Workshop Report: Facilitating Oral Product Development and Reducing Regulatory Burden Through Novel Approaches to Assess Bioavailability/Bioequivalence

Por Polli, James E., Cook, Jack A., Davit, Barbara M., Dickinson, Paul A., Argenti, Domenick, Barbour, Nancy, García-Arieta, Alfredo, Geoffroy, Jean-Marie, Hartauer, Kerry, Li, Shoufeng, Mitra, Amitava, Muller, Francis X., Purohit, Vivek, Sanchez-Felix, Manuel, Skoug, John W., Tang, Kin
Publicado em 2012