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Interaction of dicaproyl phosphatidylserine with recombinant factor VIII and its impact on immunogenicity

Replacement therapy with exogenous recombinant factor VIII (rFVIII) to control bleeding episodes results in the development of inhibitory antibodies in 15% to 30% of hemophilia A patients. The inhibitory antibodies are mainly directed against specific and universal immunodominant epitopes located in...

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Detalhes bibliográficos
Main Authors: Purohit, Vivek S., Balasubramanian, Sathyamangalam V.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574005/
https://ncbi.nlm.nih.gov/pubmed/16796387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF02854907
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