SG-04 THE eEF2 KINASE, A MEDIATOR OF MEDULLOBLASTOMA ADAPTATION TO METABOLIC STRESS, SUPPORTS FATTY ACID OXIDATION

Por Leprivier, Gabriel, Teperino, Raffaele, Kristensen, Anders, Remke, Marc, Pfister, Stefan, Taylor, Michael D., Pospisilik, J. Andrew, Sorensen, Poul H.
Publicado no Neuro Oncol (2015)

Islet Macrophages Shift to a Reparative State following Pancreatic Beta-Cell Death and Are a Major Source of Islet Insulin-like Growth Factor-1

Por Nackiewicz, Dominika, Dan, Meixia, Speck, Madeleine, Chow, Samuel Z., Chen, Yi-Chun, Pospisilik, J. Andrew, Verchere, C. Bruce, Ehses, Jan A.
Publicado no iScience (2019)

Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson’s Disease

Por Li, Peipei, Killinger, Bryan A., Ensink, Elizabeth, Beddows, Ian, Yilmaz, Ali, Lubben, Noah, Lamp, Jared, Schilthuis, Meghan, Vega, Irving E., Woltjer, Randy, Pospisilik, J. Andrew, Brundin, Patrik, Brundin, Lena, Graham, Stewart F., Labrie, Viviane
Publicado no Metabolites (2021)

Cross-Talk Between Interferon-γ and Hedgehog Signaling Regulates Adipogenesis

Por Todoric, Jelena, Strobl, Birgit, Jais, Alexander, Boucheron, Nicole, Bayer, Martina, Amann, Sabine, Lindroos, Josefine, Teperino, Raffaele, Prager, Gerhard, Bilban, Martin, Ellmeier, Wilfried, Krempler, Franz, Müller, Mathias, Wagner, Oswald, Patsch, Wolfgang, Pospisilik, J. Andrew, Esterbauer, Harald
Publicado em 2011

In vivo genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection

Por Cronin, Shane J. F., Nehme, Nadine T., Limmer, Stefanie, Liegeois, Samuel, Pospisilik, J. Andrew, Schramek, Daniel, Leibbrandt, Andreas, Simoes, Ricardo de Matos, Gruber, Susanne, Puc, Urszula, Ebersberger, Ingo, Zoranovic, Tamara, Neely, G. Gregory, von Haeseler, Arndt, Ferrandon, Dominique, Penninger, Josef M.
Publicado em 2009

Human but Not Mouse Adipogenesis Is Critically Dependent on LMO3

Por Lindroos, Josefine, Husa, Julia, Mitterer, Gerfried, Haschemi, Arvand, Rauscher, Sabine, Haas, Robert, Gröger, Marion, Loewe, Robert, Kohrgruber, Norbert, Schrögendorfer, Klaus F., Prager, Gerhard, Beck, Harald, Pospisilik, J. Andrew, Zeyda, Maximilian, Stulnig, Thomas M., Patsch, Wolfgang, Wagner, Oswald, Esterbauer, Harald, Bilban, Martin
Publicado em 2013

Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity

Por Timper, Katharina, Paeger, Lars, Sánchez-Lasheras, Carmen, Varela, Luis, Jais, Alexander, Nolte, Hendrik, Vogt, Merly C., Hausen, A. Christine, Heilinger, Christian, Evers, Nadine, Pospisilik, J. Andrew, Penninger, Josef M., Taylor, Eric B., Horvath, Tamas L., Kloppenburg, Peter, Brüning, Jens Claus
Publicado no Cell Rep (2018)

The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism

Por Haschemi, Arvand, Kosma, Paul, Gille, Lars, Evans, Charles R., Burant, Charles F., Starkl, Philipp, Knapp, Bernhard, Haas, Robert, Schmid, Johannes A., Jandl, Christoph, Amir, Shahzada, Lubec, Gert, Park, Jaehong, Esterbauer, Harald, Bilban, Martin, Brizuela, Leonardo, Pospisilik, J. Andrew, Otterbein, Leo E., Wagner, Oswald
Publicado em 2012

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD(+) consumption

Por Posavec Marjanović, Melanija, Hurtado-Bagès, Sarah, Lassi, Maximilian, Valero, Vanesa, Malinverni, Roberto, Delage, Hélène, Navarro, Miriam, Corujo, David, Guberovic, Iva, Douet, Julien, Gama-Perez, Pau, Garcia-Roves, Pablo M., Ahel, Ivan, Ladurner, Andreas G., Yanes, Oscar, Bouvet, Philippe, Suelves, Mònica, Teperino, Raffaele, Pospisilik, J. Andrew, Buschbeck, Marcus
Publicado no Nat Struct Mol Biol (2017)

Impairment of Hepatic Growth Hormone and Glucocorticoid Receptor Signaling Causes Steatosis and Hepatocellular Carcinoma in Mice

Por Mueller, Kristina M, Kornfeld, Jan-Wilhelm, Friedbichler, Katrin, Blaas, Leander, Egger, Gerda, Esterbauer, Harald, Hasselblatt, Peter, Schlederer, Michaela, Haindl, Susanne, Wagner, Kay-Uwe, Engblom, David, Haemmerle, Guenter, Kratky, Dagmar, Sexl, Veronika, Kenner, Lukas, Kozlov, Andrey V, Terracciano, Luigi, Zechner, Rudolf, Schuetz, Guenther, Casanova, Emilio, Pospisilik, J Andrew, Heim, Markus H, Moriggl, Richard
Publicado em 2011

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes

Por Lu, Tess Tsai-Hsiu, Heyne, Steffen, Dror, Erez, Casas, Eduard, Leonhardt, Laura, Boenke, Thorina, Yang, Chih-Hsiang, Sagar, Arrigoni, Laura, Dalgaard, Kevin, Teperino, Raffaele, Enders, Lennart, Selvaraj, Madhan, Ruf, Marius, Raja, Sunil J., Xie, Huafeng, Boenisch, Ulrike, Orkin, Stuart H., Lynn, Francis C., Hoffman, Brad G., Grün, Dominic, Vavouri, Tanya, Lempradl, Adelheid M., Pospisilik, J. Andrew
Publicado no Cell Metab (2018)

Construction of a Global Pain Systems Network Highlights Phospholipid Signaling as a Regulator of Heat Nociception

Por Neely, G. Gregory, Rao, Shuan, Costigan, Michael, Mair, Norbert, Racz, Ildiko, Milinkeviciute, Giedre, Meixner, Arabella, Nayanala, Swetha, Griffin, Robert S., Belfer, Inna, Dai, Feng, Smith, Shad, Diatchenko, Luda, Marengo, Stefano, Haubner, Bernhard J., Novatchkova, Maria, Gibson, Dustin, Maixner, William, Pospisilik, J. Andrew, Hirsch, Emilio, Whishaw, Ian Q., Zimmer, Andreas, Gupta, Vaijayanti, Sasaki, Junko, Kanaho, Yasunori, Sasaki, Takehiko, Kress, Michaela, Woolf, Clifford J., Penninger, Josef M.
Publicado em 2012

Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity

Por Dalgaard, Kevin, Landgraf, Kathrin, Heyne, Steffen, Lempradl, Adelheid, Longinotto, John, Gossens, Klaus, Ruf, Marius, Orthofer, Michael, Strogantsev, Ruslan, Selvaraj, Madhan, Lu, Tess Tsai-Hsiu, Casas, Eduard, Teperino, Raffaele, Surani, M. Azim, Zvetkova, Ilona, Rimmington, Debra, Tung, Y.C. Loraine, Lam, Brian, Larder, Rachel, Yeo, Giles S.H., O’Rahilly, Stephen, Vavouri, Tanya, Whitelaw, Emma, Penninger, Josef M., Jenuwein, Thomas, Cheung, Ching-Lung, Ferguson-Smith, Anne C., Coll, Anthony P., Körner, Antje, Pospisilik, J. Andrew
Publicado no Cell (2016)

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function

Por Neely, G. Gregory, Kuba, Keiji, Cammarato, Anthony, Isobe, Kazuya, Amann, Sabine, Zhang, Liyong, Murata, Mitsushige, Elmén, Lisa, Gupta, Vaijayanti, Arora, Suchir, Sarangi, Rinku, Dan, Debasis, Fujisawa, Susumu, Usami, Takako, Xia, Cui-ping, Keene, Alex C., Alayari, Nakissa N., Yamakawa, Hiroyuki, Elling, Ulrich, Berger, Christian, Novatchkova, Maria, Koglgruber, Rubina, Fukuda, Keiichi, Nishina, Hiroshi, Isobe, Mitsuaki, Pospisilik, J. Andrew, Imai, Yumiko, Pfeufer, Arne, Hicks, Andrew A, Pramstaller, Peter P., Subramaniam, Sai, Kimura, Akinori, Ocorr, Karen, Bodmer, Rolf, Penninger, Josef M.
Publicado em 2010

Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man

Por Jais, Alexander, Einwallner, Elisa, Sharif, Omar, Gossens, Klaus, Lu, Tess Tsai-Hsiu, Soyal, Selma M., Medgyesi, David, Neureiter, Daniel, Paier-Pourani, Jamile, Dalgaard, Kevin, Duvigneau, J. Catharina, Lindroos-Christensen, Josefine, Zapf, Thea-Christin, Amann, Sabine, Saluzzo, Simona, Jantscher, Florian, Stiedl, Patricia, Todoric, Jelena, Martins, Rui, Oberkofler, Hannes, Müller, Simone, Hauser-Kronberger, Cornelia, Kenner, Lukas, Casanova, Emilio, Sutterlüty-Fall, Hedwig, Bilban, Martin, Miller, Karl, Kozlov, Andrey V., Krempler, Franz, Knapp, Sylvia, Lumeng, Carey N., Patsch, Wolfgang, Wagner, Oswald, Pospisilik, J. Andrew, Esterbauer, Harald
Publicado no Cell (2014)

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

Por Neely, G. Gregory, Hess, Andreas, Costigan, Michael, Keene, Alex C., Goulas, Spyros, Langeslag, Michiel, Griffin, Robert S, Belfer, Inna, Dai, Feng, Smith, Shad, Diatchenko, Luda, Gupta, Vaijayanti, Xia, Cui-ping, Amann, Sabina, Kreitz, Silke, Heindl-Erdmann, Cornelia, Wolz, Susanne, Ly, Cindy V., Arora, Suchir, Sarangi, Rinku, Dan, Debasis, Novatchkova, Maria, Rosenzweig, Mark, Gibson, Dustin, Truong, Darwin, Schramek, Daniel, Zoranovic, Tamara, Cronin, Shane J. F., Angjeli, Belinda, Brune, Kay, Dietzl, Georg, Maixner, William, Meixner, Arabella, Thomas, Winston, Pospisilik, J. Andrew, Alenius, Mattias, Kress, Michaela, Subramaniam, Sai, Garrity, Paul A., Bellen, Hugo J., Woolf, Clifford J., Penninger, Josef M.
Publicado em 2010

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

Por Justice, Anne E, Karaderi, Tugce, Highland, Heather M, Young, Kristin L, Graff, Mariaelisa, Lu, Yingchang, Turcot, Valérie, Auer, Paul L, Fine, Rebecca S, Guo, Xiuqing, Schurmann, Claudia, Lempradl, Adelheid, Marouli, Eirini, Mahajan, Anubha, Winkler, Thomas W, Locke, Adam E, Medina-Gomez, Carolina, Esko, Tõnu, Vedantam, Sailaja, Giri, Ayush, Lo, Ken Sin, Alfred, Tamuno, Mudgal, Poorva, Ng, Maggie CY, Heard-Costa, Nancy L, Feitosa, Mary F, Manning, Alisa K, Willems, Sara M, Sivapalaratnam, Suthesh, Abecasis, Goncalo, Alam, Dewan S, Allison, Matthew, Amouyel, Philippe, Arzumanyan, Zorayr, Balkau, Beverley, Bastarache, Lisa, Bergmann, Sven, Bielak, Lawrence F, Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A, Bork-Jensen, Jette, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Broer, Linda, Burt, Amber A, Butterworth, Adam S, Caulfield, Mark J, Cesana, Giancarlo, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Collins, Francis S, Cook, James P, Cox, Amanda J, Crosslin, David S, Danesh, John, de Bakker, Paul IW, de Denus, Simon, de Mutsert, Renée, Dedoussis, George, Demerath, Ellen W, Dennis, Joe G, Denny, Josh C, Di Angelantonio, Emanuele, Dörr, Marcus, Drenos, Fotios, Dubé, Marie-Pierre, Dunning, Alison M, Easton, Douglas F, Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Feng, Shuang, Ferrannini, Ele, Ferrieres, Jean, Florez, Jose C, Fornage, Myriam, Fox, Caroline S, Franks, Paul W, Friedrich, Nele, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Girotto, Giorgia, Gorski, Mathias, Grallert, Harald, Grarup, Niels, Grove, Megan L, Gustafsson, Stefan, Haessler, Jeff, Hansen, Torben, Hattersley, Andrew T, Hayward, Caroline, Heid, Iris M, Holmen, Oddgeir L, Hovingh, G Kees, Howson, Joanna MM, Hu, Yao, Hung, Yi-Jen, Hveem, Kristian, Ikram, M Arfan, Ingelsson, Erik, Jackson, Anne U, Jarvik, Gail P, Jia, Yucheng, Jørgensen, Torben, Jousilahti, Pekka, Justesen, Johanne M, Kahali, Bratati, Karaleftheri, Maria, Kardia, Sharon LR, Karpe, Fredrik, Kee, Frank, Kitajima, Hidetoshi, Komulainen, Pirjo, Kooner, Jaspal S, Kovacs, Peter, Krämer, Bernhard K, Kuulasmaa, Kari, Kuusisto, Johanna, Laakso, Markku, Lakka, Timo A, Lamparter, David, Lange, Leslie A, Langenberg, Claudia, Larson, Eric B, Lee, Nanette R, Lee, Wen-Jane, Lehtimäki, Terho, Lewis, Cora E, Li, Huaixing, Li, Jin, Li-Gao, Ruifang, Lin, Li-An, Lin, Xu, Lind, Lars, Lindström, Jaana, Linneberg, Allan, Liu, Ching-Ti, Liu, Dajiang J, Luan, Jian’an, Lyytikäinen, Leo-Pekka, MacGregor, Stuart, Mägi, Reedik, Männistö, Satu, Marenne, Gaëlle, Marten, Jonathan, Masca, Nicholas GD, McCarthy, Mark I, Meidtner, Karina, Mihailov, Evelin, Moilanen, Leena, Moitry, Marie, Mook-Kanamori, Dennis O, Morgan, Anna, Morris, Andrew P, Müller-Nurasyid, Martina, Munroe, Patricia B, Narisu, Narisu, Nelson, Christopher P, Neville, Matt, Ntalla, Ioanna, O’Connell, Jeffrey R, Owen, Katharine R, Pedersen, Oluf, Peloso, Gina M, Pennell, Craig E, Perola, Markus, Perry, James A, Perry, John RB, Pers, Tune H, Ewing, Ailith, Polasek, Ozren, Raitakari, Olli T, Rasheed, Asif, Raulerson, Chelsea K, Rauramaa, Rainer, Reilly, Dermot F, Reiner, Alex P, Ridker, Paul M, Rivas, Manuel A, Robertson, Neil R, Robino, Antonietta, Rudan, Igor, Ruth, Katherine S, Saleheen, Danish, Salomaa, Veikko, Samani, Nilesh J, Schreiner, Pamela J, Schulze, Matthias B, Scott, Robert A, Segura-Lepe, Marcelo, Sim, Xueling, Slater, Andrew J, Small, Kerrin S, Smith, Blair H, Smith, Jennifer A, Southam, Lorraine, Spector, Timothy D, Speliotes, Elizabeth K, Stefansson, Kari, Steinthorsdottir, Valgerdur, Stirrups, Kathleen E, Strauch, Konstantin, Stringham, Heather M, Stumvoll, Michael, Sun, Liang, Surendran, Praveen, Swart, Karin MA, Tardif, Jean-Claude, Taylor, Kent D, Teumer, Alexander, Thompson, Deborah J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Thuesen, Betina H, Tönjes, Anke, Torres, Mina, Tsafantakis, Emmanouil, Tuomilehto, Jaakko, Uitterlinden, André G, Uusitupa, Matti, van Duijn, Cornelia M, Vanhala, Mauno, Varma, Rohit, Vermeulen, Sita H, Vestergaard, Henrik, Vitart, Veronique, Vogt, Thomas F, Vuckovic, Dragana, Wagenknecht, Lynne E, Walker, Mark, Wallentin, Lars, Wang, Feijie, Wang, Carol A, Wang, Shuai, Wareham, Nicholas J, Warren, Helen R, Waterworth, Dawn M, Wessel, Jennifer, White, Harvey D, Willer, Cristen J, Wilson, James G, Wood, Andrew R, Wu, Ying, Yaghootkar, Hanieh, Yao, Jie, Yerges-Armstrong, Laura M, Young, Robin, Zeggini, Eleftheria, Zhan, Xiaowei, Zhang, Weihua, Zhao, Jing Hua, Zhao, Wei, Zheng, He, Zhou, Wei, Zillikens, M Carola, Rivadeneira, Fernando, Borecki, Ingrid B, Pospisilik, J. Andrew, Deloukas, Panos, Frayling, Timothy M, Lettre, Guillaume, Mohlke, Karen L, Rotter, Jerome I, Kutalik, Zoltán, Hirschhorn, Joel N, Cupples, L Adrienne, Loos, Ruth JF, North, Kari E, Lindgren, Cecilia M
Publicado no Nat Genet (2019)