Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

door Burgess, Stephen, Butterworth, Adam, Thompson, Simon G
Gepubliceerd in Genet Epidemiol (2013)

Beyond Mendelian randomization: how to interpret evidence of shared genetic predictors

door Burgess, Stephen, Butterworth, Adam S., Thompson, John R.
Gepubliceerd in J Clin Epidemiol (2016)

Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways

door Burgess, Stephen, Daniel, Rhian M, Butterworth, Adam S, Thompson, Simon G
Gepubliceerd in Int J Epidemiol (2015)

Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis

door Haycock, Philip C, Heydon, Emma E, Kaptoge, Stephen, Butterworth, Adam S, Thompson, Alex, Willeit, Peter
Gepubliceerd in 2014

High-throughput multivariable Mendelian randomization analysis prioritizes apolipoprotein B as key lipid risk factor for coronary artery disease

door Zuber, Verena, Gill, Dipender, Ala-Korpela, Mika, Langenberg, Claudia, Butterworth, Adam, Bottolo, Leonardo, Burgess, Stephen
Gepubliceerd in Int J Epidemiol (2020)

Lipoprotein(a) in Alzheimer’s, Atherosclerotic, Cerebrovascular, Thrombotic, and Valvular Disease: Mendelian Randomization Investigation

door Larsson, Susanna C., Gill, Dipender, Mason, Amy M., Jiang, Tao, Bäck, Magnus, Butterworth, Adam S., Burgess, Stephen
Gepubliceerd in Circulation (2020)

Genetically Predicted Plasma Cortisol and Common Chronic Diseases: A Mendelian Randomization Study

door Lee, Wei-Hsuan, Larsson, Susanna C., Wood, Angela, Di Angelantonio, Emanuele, Butterworth, Adam S., Burgess, Stephen, Allara, Elias
Gepubliceerd in Clin Endocrinol (Oxf) (2023)

A comparison of Cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design

door Staley, James R, Jones, Edmund, Kaptoge, Stephen, Butterworth, Adam S, Sweeting, Michael J, Wood, Angela M, Howson, Joanna M M
Gepubliceerd in Eur J Hum Genet (2017)

PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations

door Kamat, Mihir A, Blackshaw, James A, Young, Robin, Surendran, Praveen, Burgess, Stephen, Danesh, John, Butterworth, Adam S, Staley, James R
Gepubliceerd in Bioinformatics (2019)

ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci

door Stacey, David, Fauman, Eric B, Ziemek, Daniel, Sun, Benjamin B, Harshfield, Eric L, Wood, Angela M, Butterworth, Adam S, Suhre, Karsten, Paul, Dirk S
Gepubliceerd in Nucleic Acids Res (2019)

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

door Abraham, Gad, Malik, Rainer, Yonova-Doing, Ekaterina, Salim, Agus, Wang, Tingting, Danesh, John, Butterworth, Adam S., Howson, Joanna M. M., Inouye, Michael, Dichgans, Martin
Gepubliceerd in Nat Commun (2019)

Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

door Abraham, Gad, Malik, Rainer, Yonova-Doing, Ekaterina, Salim, Agus, Wang, Tingting, Danesh, John, Butterworth, Adam S., Howson, Joanna M. M., Inouye, Michael, Dichgans, Martin
Gepubliceerd in Nat Commun (2020)

Leucocyte Telomere Length and Risk of Type 2 Diabetes Mellitus: New Prospective Cohort Study and Literature-Based Meta-Analysis

door Willeit, Peter, Raschenberger, Julia, Heydon, Emma E., Tsimikas, Sotirios, Haun, Margot, Mayr, Agnes, Weger, Siegfried, Witztum, Joseph L., Butterworth, Adam S., Willeit, Johann, Kronenberg, Florian, Kiechl, Stefan
Gepubliceerd in PLoS One (2014)

PhenoScanner: a database of human genotype–phenotype associations

door Staley, James R., Blackshaw, James, Kamat, Mihir A., Ellis, Steve, Surendran, Praveen, Sun, Benjamin B., Paul, Dirk S., Freitag, Daniel, Burgess, Stephen, Danesh, John, Young, Robin, Butterworth, Adam S.
Gepubliceerd in Bioinformatics (2016)

Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis

door Kaptoge, Stephen, Seshasai, Sreenivasa Rao Kondapally, Gao, Pei, Freitag, Daniel F., Butterworth, Adam S., Borglykke, Anders, Di Angelantonio, Emanuele, Gudnason, Vilmundur, Rumley, Ann, Lowe, Gordon D.O., Jørgensen, Torben, Danesh, John
Gepubliceerd in 2014

Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases: A Mendelian Randomization Study

door Donovan, Killian, Herrington, William G., Paré, Guillaume, Pigeyre, Marie, Haynes, Richard, Sardell, Rebecca, Butterworth, Adam S., Folkersen, Lasse, Gustafsson, Stefan, Wang, Qin, Baigent, Colin, Mälarstig, Anders, Holmes, Michael V., Staplin, Natalie
Gepubliceerd in Clin J Am Soc Nephrol (2022)

Polygenic risk score identifies subgroup with higher burden of atherosclerosis and greater relative benefit from statin therapy in the primary prevention setting

door Natarajan, Pradeep, Young, Robin, Stitziel, Nathan O., Padmanabhan, Sandosh, Baber, Usman, Mehran, Roxana, Sartori, Samantha, Fuster, Valentin, Reilly, Dermot F., Butterworth, Adam, Rader, Daniel J., Ford, Ian, Sattar, Naveed, Kathiresan, Sekar
Gepubliceerd in Circulation (2017)

The influence of rare variants in circulating metabolic biomarkers

door Riveros-Mckay, Fernando, Oliver-Williams, Clare, Karthikeyan, Savita, Walter, Klaudia, Kundu, Kousik, Ouwehand, Willem H., Roberts, David, Di Angelantonio, Emanuele, Soranzo, Nicole, Danesh, John, Wheeler, Eleanor, Zeggini, Eleftheria, Butterworth, Adam S., Barroso, Inês
Gepubliceerd in PLoS Genet (2020)

Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis

door Wang, Qin, Oliver-Williams, Clare, Raitakari, Olli T, Viikari, Jorma, Lehtimäki, Terho, Kähönen, Mika, Järvelin, Marjo-Riitta, Salomaa, Veikko, Perola, Markus, Danesh, John, Kettunen, Johannes, Butterworth, Adam S, Holmes, Michael V, Ala-Korpela, Mika
Gepubliceerd in Eur Heart J (2020)

Effect of communicating phenotypic and genetic risk of coronary heart disease alongside web-based lifestyle advice: the INFORM Randomised Controlled Trial

door Silarova, Barbora, Sharp, Stephen, Usher-Smith, Juliet A, Lucas, Joanne, Payne, Rupert A, Shefer, Guy, Moore, Carmel, Girling, Christine, Lawrence, Kathryn, Tolkien, Zoe, Walker, Matthew, Butterworth, Adam, Di Angelantonio, Emanuele, Danesh, John, Griffin, Simon J
Gepubliceerd in Heart (2019)