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Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways
Background: Mendelian randomization uses genetic variants, assumed to be instrumental variables for a particular exposure, to estimate the causal effect of that exposure on an outcome. If the instrumental variable criteria are satisfied, the resulting estimator is consistent even in the presence of...
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| Publicat a: | Int J Epidemiol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469795/ https://ncbi.nlm.nih.gov/pubmed/25150977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyu176 |
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