Loading...

Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways

Background: Mendelian randomization uses genetic variants, assumed to be instrumental variables for a particular exposure, to estimate the causal effect of that exposure on an outcome. If the instrumental variable criteria are satisfied, the resulting estimator is consistent even in the presence of...

Full description

Saved in:
Bibliographic Details
Published in:Int J Epidemiol
Main Authors: Burgess, Stephen, Daniel, Rhian M, Butterworth, Adam S, Thompson, Simon G
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469795/
https://ncbi.nlm.nih.gov/pubmed/25150977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyu176
Tags: Add Tag
No Tags, Be the first to tag this record!