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Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways
Background: Mendelian randomization uses genetic variants, assumed to be instrumental variables for a particular exposure, to estimate the causal effect of that exposure on an outcome. If the instrumental variable criteria are satisfied, the resulting estimator is consistent even in the presence of...
Shranjeno v:
| izdano v: | Int J Epidemiol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469795/ https://ncbi.nlm.nih.gov/pubmed/25150977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyu176 |
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