Targeting Mutant Fibroblast Growth Factor Receptors in Cancer

door Greulich, Heidi, Pollock, Pamela M.
Gepubliceerd in 2011

Lineage specific biomarkers predict response to FGFR inhibition

door Loch, David C., Pollock, Pamela M.
Gepubliceerd in Cancer Discov (2012)

Fibroblast Growth Factor Receptor 2 Isoforms Detected via Novel RNA ISH as Predictive Biomarkers for Progestin Therapy in Atypical Hyperplasia and Low-Grade Endometrial Cancer

door Sengal, Asmerom T., Smith, Deborah, Rogers, Rebecca, Snell, Cameron E., Williams, Elizabeth D., Pollock, Pamela M.
Gepubliceerd in Cancers (Basel) (2021)

Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk

door Zhao, Zhen Zhen, Pollock, Pamela M., Thomas, Shane, Treloar, Susan A., Nyholt, Dale R., Montgomery, Grant W.
Gepubliceerd in 2008

Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation

door Karlsson, Thomas, Krakstad, Camilla, Tangen, Ingvild Løberg, Hoivik, Erling A., Pollock, Pamela M., Salvesen, Helga B., Lewis, Aurélia E.
Gepubliceerd in Oncotarget (2016)

Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status

door Byron, Sara A, Loch, David C, Wellens, Candice L, Wortmann, Andreas, Wu, Jiayi, Wang, John, Nomoto, Kenichi, Pollock, Pamela M
Gepubliceerd in 2012

Cellular Settings Mediating Src Substrate Switching between Focal Adhesion Kinase Tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) Tyrosine 734

door Wortmann, Andreas, He, Yaowu, Christensen, Melinda E., Linn, MayLa, Lumley, John W., Pollock, Pamela M., Waterhouse, Nigel J., Hooper, John D.
Gepubliceerd in 2011

FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features

door Byron, Sara A., Gartside, Michael, Powell, Matthew A., Wellens, Candice L., Gao, Feng, Mutch, David G., Goodfellow, Paul J., Pollock, Pamela M.
Gepubliceerd in 2012

Correction: FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features

door Byron, Sara A., Gartside, Michael, Powell, Matthew A., Wellens, Candice L., Gao, Feng, Mutch, David G., Goodfellow, Paul J., Pollock, Pamela M.
Gepubliceerd in 2012

The ‘melanoma-enriched’ microRNA miR-4731-5p acts as a tumour suppressor

door Stark, Mitchell S., Tom, Lisa N., Boyle, Glen M., Bonazzi, Vanessa F., Soyer, H. Peter, Herington, Adrian C., Pollock, Pamela M., Hayward, Nicholas K.
Gepubliceerd in Oncotarget (2016)

Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo

door Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas, McGovern, Jacqui A.
Gepubliceerd in Bone Res (2019)

Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo

door Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas, McGovern, Jacqui A.
Gepubliceerd in Bone Res (2020)

A crystallographic snapshot of tyrosine trans-phosphorylation in action

door Chen, Huaibin, Xu, Chong-Feng, Ma, Jinghong, Eliseenkova, Anna V., Li, Wanqing, Pollock, Pamela M., Pitteloud, Nelly, Miller, W. Todd, Neubert, Thomas A., Mohammadi, Moosa
Gepubliceerd in 2008

The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors

door Byron, Sara A, Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G, Dehkhoda, Farhad, Blais, Steven P, Neubert, Thomas A, Mohammadi, Moosa, Pollock, Pamela M
Gepubliceerd in 2013

Bcl‐2 inhibitors enhance FGFR inhibitor‐induced mitochondrial‐dependent cell death in FGFR2‐mutant endometrial cancer

door Packer, Leisl M., Stehbens, Samantha J., Bonazzi, Vanessa F., Gunter, Jennifer H., Ju, Robert J., Ward, Micheal, Gartside, Michael G., Byron, Sara A., Pollock, Pamela M.
Gepubliceerd in Mol Oncol (2019)

Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia

door Kane, Alexandra M., Liu, Cheng, Fennell, Lochlan J., McKeone, Diane M., Bond, Catherine E., Pollock, Pamela M., Young, Graeme, Leggett, Barbara A., Whitehall, Vicki L. J.
Gepubliceerd in Br J Cancer (2021)

Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen

door Bhatia, Sugandha, Blick, Tony, Pinto, Cletus, Waltham, Mark, Monkman, James, Ivanova, Ekaterina, Pollock, Pamela M., Nagaraj, Shivashankar H., Wiegmans, Adrian P., Haviv, Izhak, Simpson, Kaylene J., Thompson, Erik W.
Gepubliceerd in Cancers (Basel) (2020)

miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma

door Stark, Mitchell S., Bonazzi, Vanessa F., Boyle, Glen M., Palmer, Jane M., Symmons, Judith, Lanagan, Catherine M., Schmidt, Christopher W., Herington, Adrian C., Ballotti, Robert, Pollock, Pamela M., Hayward, Nicholas K.
Gepubliceerd in Oncotarget (2015)

Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix

door Kalinina, Juliya, Byron, Sara A., Makarenkova, Helen P., Olsen, Shaun K., Eliseenkova, Anna V., Larochelle, William J., Dhanabal, Mohanraj, Blais, Steven, Ornitz, David M., Day, Loren A., Neubert, Thomas A., Pollock, Pamela M., Mohammadi, Moosa
Gepubliceerd in 2009

A Phase II Trial of Brivanib in Recurrent or Persistent Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study

door Powell, Matthew A., Sill, Michael W., Goodfellow, Paul J., Benbrook, Doris M., Lankes, Heather A., Leslie, Kimberly K., Jeske, Yvette, Mannel, Robert S., Spillman, Monique A, Lee, Paula S., Hoffman, James S., McMeekin, D. Scott, Pollock, Pamela M.
Gepubliceerd in Gynecol Oncol (2014)