New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways

Por He, Yaowu, Harrington, Brittney S., Hooper, John D.
Publicado no Oncoscience (2016)

MB-58 TARGETING APOPTOSIS AS A NOVEL THERAPY FOR MYC-DRIVEN MEDULLOBLASTOMA

Por Ji, Pengxiang, Genovesi, Laura, He, Yaowu, Hooper, John, Wainwright, Brandon
Publicado no Neuro Oncol (2016)

The Role of Palmitoylation in Signalling, Cellular Trafficking and Plasma Membrane Localization of Protease-Activated Receptor-2

Por Adams, Mark N., Christensen, Melinda E., He, Yaowu, Waterhouse, Nigel J., Hooper, John D.
Publicado em 2011

Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization via PARP1-mediated apoptosis of cancer cells

Por Casar, Berta, He, Yaowu, Iconomou, Mary, Hooper, John D., Quigley, James P., Deryugina, Elena I.
Publicado no Oncogene (2011)

The Cell Surface Glycoprotein CUB Domain-containing Protein 1 (CDCP1) Contributes to Epidermal Growth Factor Receptor-mediated Cell Migration

Por Dong, Ying, He, Yaowu, de Boer, Leonore, Stack, M. Sharon, Lumley, John W., Clements, Judith A., Hooper, John D.
Publicado em 2012

The Ubiquitin-Protein Ligase Nedd4-2 Differentially Interacts with and Regulates Members of the Tweety Family of Chloride Ion Channels

Por He, Yaowu, Hryciw, Deanne H., Carroll, Melanie L., Myers, Stephen A., Whitbread, Astrid K., Kumar, Sharad, Poronnik, Philip, Hooper, John D.
Publicado em 2008

Cellular Settings Mediating Src Substrate Switching between Focal Adhesion Kinase Tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) Tyrosine 734

Por Wortmann, Andreas, He, Yaowu, Christensen, Melinda E., Linn, MayLa, Lumley, John W., Pollock, Pamela M., Waterhouse, Nigel J., Hooper, John D.
Publicado em 2011

Proteolysis-induced N-terminal Ectodomain Shedding of the Integral Membrane Glycoprotein CUB Domain-containing Protein 1 (CDCP1) Is Accompanied by Tyrosine Phosphorylation of Its C...

Por He, Yaowu, Wortmann, Andreas, Burke, Les J., Reid, Janet C., Adams, Mark N., Abdul-Jabbar, Ibtissam, Quigley, James P., Leduc, Richard, Kirchhofer, Daniel, Hooper, John D.
Publicado em 2010

Potent Small Agonists of Protease Activated Receptor 2

Por Yau, Mei-Kwan, Suen, Jacky Y., Xu, Weijun, Lim, Junxian, Liu, Ligong, Adams, Mark N., He, Yaowu, Hooper, John D., Reid, Robert C., Fairlie, David P.
Publicado no ACS Med Chem Lett (2015)

Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer

Por Harrington, Brittney S, He, Yaowu, Davies, Claire M, Wallace, Sarah J, Adams, Mark N, Beaven, Elizabeth A, Roche, Deborah K, Kennedy, Catherine, Chetty, Naven P, Crandon, Alexander J, Flatley, Christopher, Oliveira, Niara B, Shannon, Catherine M, deFazio, Anna, Tinker, Anna V, Gilks, C Blake, Gabrielli, Brian, Brennan, Donal J, Coward, Jermaine I, Armes, Jane E, Perrin, Lewis C, Hooper, John D
Publicado no Br J Cancer (2016)