Targeting Mutant Fibroblast Growth Factor Receptors in Cancer

di Greulich, Heidi, Pollock, Pamela M.
Pubblicazione 2011

Lineage specific biomarkers predict response to FGFR inhibition

di Loch, David C., Pollock, Pamela M.
Pubblicato in Cancer Discov (2012)

Fibroblast Growth Factor Receptor 2 Isoforms Detected via Novel RNA ISH as Predictive Biomarkers for Progestin Therapy in Atypical Hyperplasia and Low-Grade Endometrial Cancer

di Sengal, Asmerom T., Smith, Deborah, Rogers, Rebecca, Snell, Cameron E., Williams, Elizabeth D., Pollock, Pamela M.
Pubblicato in Cancers (Basel) (2021)

Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk

di Zhao, Zhen Zhen, Pollock, Pamela M., Thomas, Shane, Treloar, Susan A., Nyholt, Dale R., Montgomery, Grant W.
Pubblicazione 2008

Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation

di Karlsson, Thomas, Krakstad, Camilla, Tangen, Ingvild Løberg, Hoivik, Erling A., Pollock, Pamela M., Salvesen, Helga B., Lewis, Aurélia E.
Pubblicato in Oncotarget (2016)

Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status

di Byron, Sara A, Loch, David C, Wellens, Candice L, Wortmann, Andreas, Wu, Jiayi, Wang, John, Nomoto, Kenichi, Pollock, Pamela M
Pubblicazione 2012

Cellular Settings Mediating Src Substrate Switching between Focal Adhesion Kinase Tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) Tyrosine 734

di Wortmann, Andreas, He, Yaowu, Christensen, Melinda E., Linn, MayLa, Lumley, John W., Pollock, Pamela M., Waterhouse, Nigel J., Hooper, John D.
Pubblicazione 2011

FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features

di Byron, Sara A., Gartside, Michael, Powell, Matthew A., Wellens, Candice L., Gao, Feng, Mutch, David G., Goodfellow, Paul J., Pollock, Pamela M.
Pubblicazione 2012

Correction: FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features

di Byron, Sara A., Gartside, Michael, Powell, Matthew A., Wellens, Candice L., Gao, Feng, Mutch, David G., Goodfellow, Paul J., Pollock, Pamela M.
Pubblicazione 2012

The ‘melanoma-enriched’ microRNA miR-4731-5p acts as a tumour suppressor

di Stark, Mitchell S., Tom, Lisa N., Boyle, Glen M., Bonazzi, Vanessa F., Soyer, H. Peter, Herington, Adrian C., Pollock, Pamela M., Hayward, Nicholas K.
Pubblicato in Oncotarget (2016)

Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo

di Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas, McGovern, Jacqui A.
Pubblicato in Bone Res (2019)

Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo

di Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas, McGovern, Jacqui A.
Pubblicato in Bone Res (2020)

A crystallographic snapshot of tyrosine trans-phosphorylation in action

di Chen, Huaibin, Xu, Chong-Feng, Ma, Jinghong, Eliseenkova, Anna V., Li, Wanqing, Pollock, Pamela M., Pitteloud, Nelly, Miller, W. Todd, Neubert, Thomas A., Mohammadi, Moosa
Pubblicazione 2008

The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors

di Byron, Sara A, Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G, Dehkhoda, Farhad, Blais, Steven P, Neubert, Thomas A, Mohammadi, Moosa, Pollock, Pamela M
Pubblicazione 2013

Bcl‐2 inhibitors enhance FGFR inhibitor‐induced mitochondrial‐dependent cell death in FGFR2‐mutant endometrial cancer

di Packer, Leisl M., Stehbens, Samantha J., Bonazzi, Vanessa F., Gunter, Jennifer H., Ju, Robert J., Ward, Micheal, Gartside, Michael G., Byron, Sara A., Pollock, Pamela M.
Pubblicato in Mol Oncol (2019)

Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia

di Kane, Alexandra M., Liu, Cheng, Fennell, Lochlan J., McKeone, Diane M., Bond, Catherine E., Pollock, Pamela M., Young, Graeme, Leggett, Barbara A., Whitehall, Vicki L. J.
Pubblicato in Br J Cancer (2021)

Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen

di Bhatia, Sugandha, Blick, Tony, Pinto, Cletus, Waltham, Mark, Monkman, James, Ivanova, Ekaterina, Pollock, Pamela M., Nagaraj, Shivashankar H., Wiegmans, Adrian P., Haviv, Izhak, Simpson, Kaylene J., Thompson, Erik W.
Pubblicato in Cancers (Basel) (2020)

miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma

di Stark, Mitchell S., Bonazzi, Vanessa F., Boyle, Glen M., Palmer, Jane M., Symmons, Judith, Lanagan, Catherine M., Schmidt, Christopher W., Herington, Adrian C., Ballotti, Robert, Pollock, Pamela M., Hayward, Nicholas K.
Pubblicato in Oncotarget (2015)

Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix

di Kalinina, Juliya, Byron, Sara A., Makarenkova, Helen P., Olsen, Shaun K., Eliseenkova, Anna V., Larochelle, William J., Dhanabal, Mohanraj, Blais, Steven, Ornitz, David M., Day, Loren A., Neubert, Thomas A., Pollock, Pamela M., Mohammadi, Moosa
Pubblicazione 2009

A Phase II Trial of Brivanib in Recurrent or Persistent Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study

di Powell, Matthew A., Sill, Michael W., Goodfellow, Paul J., Benbrook, Doris M., Lankes, Heather A., Leslie, Kimberly K., Jeske, Yvette, Mannel, Robert S., Spillman, Monique A, Lee, Paula S., Hoffman, James S., McMeekin, D. Scott, Pollock, Pamela M.
Pubblicato in Gynecol Oncol (2014)