Colorectal cancer-associated Smad4 R361 hotspot mutations boost Wnt/β-catenin signaling through enhanced Smad4-LEF1 binding

Tekijä Lanauze, Claudia B., Sehgal, Priyanka, Hayer, Katharina, Torres-Diz, Manuel, Pippin, James A, Grant, Struan F A, Thomas-Tikhonenko, Andrei
Julkaisussa Mol Cancer Res (2021)

Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density

Tekijä Chesi, Alessandra, Wagley, Yadav, Johnson, Matthew E., Manduchi, Elisabetta, Su, Chun, Lu, Sumei, Leonard, Michelle E., Hodge, Kenyaita M., Pippin, James A., Hankenson, Kurt D., Wells, Andrew D., Grant, Struan F. A.
Julkaisussa Nat Commun (2019)

3D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders.

Tekijä Su, Chun, Argenziano, Mariana, Lu, Sumei, Pippin, James A., Pahl, Matthew C., Leonard, Michelle E., Cousminer, Diana L., Johnson, Matthew E., Lasconi, Chiara, Wells, Andrew D., Chesi, Alessandra, Grant, Struan F.A.
Julkaisussa Prog Neurobiol (2021)

Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci

Tekijä Hammond, Reza K, Pahl, Matthew C, Su, Chun, Cousminer, Diana L, Leonard, Michelle E, Lu, Sumei, Doege, Claudia A, Wagley, Yadav, Hodge, Kenyaita M, Lasconi, Chiara, Johnson, Matthew E, Pippin, James A, Hankenson, Kurt D, Leibel, Rudolph L, Chesi, Alessandra, Wells, Andrew D, Grant, Struan FA
Julkaisussa eLife (2021)

Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease

Tekijä Lasconi, Chiara, Pahl, Matthew C., Cousminer, Diana L., Doege, Claudia A., Chesi, Alessandra, Hodge, Kenyaita M., Leonard, Michelle E., Lu, Sumei, Johnson, Matthew E., Su, Chun, Hammond, Reza K., Pippin, James A., Terry, Natalie A., Ghanem, Louis R., Leibel, Rudolph L., Wells, Andrew D., Grant, Struan F.A.
Julkaisussa Cell Mol Gastroenterol Hepatol (2020)

Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual

Tekijä Cousminer, Diana L., Wagley, Yadav, Pippin, James A., Elhakeem, Ahmed, Way, Gregory P., Pahl, Matthew C., McCormack, Shana E., Chesi, Alessandra, Mitchell, Jonathan A., Kindler, Joseph M., Baird, Denis, Hartley, April, Howe, Laura, Kalkwarf, Heidi J., Lappe, Joan M., Lu, Sumei, Leonard, Michelle E., Johnson, Matthew E., Hakonarson, Hakon, Gilsanz, Vicente, Shepherd, John A., Oberfield, Sharon E., Greene, Casey S., Kelly, Andrea, Lawlor, Deborah A., Voight, Benjamin F., Wells, Andrew D., Zemel, Babette S., Hankenson, Kurt D., Grant, Struan F. A.
Julkaisussa Genome Biol (2021)