Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus

द्वारा Good, Steven S., Moussa, Adel, Zhou, Xiao-Jian, Pietropaolo, Keith, Sommadossi, Jean-Pierre
में प्रकाशित PLoS One (2020)

1265. AT-527, an Oral Purine Nucleotide Prodrug Exhibiting Potent In Vitro Antiviral Activity Against Human Coronaviruses, Including SARS-CoV-2

द्वारा Good, Steven S, Moussa, Adel, Zhou, Xiao-Jian, Pietropaolo, Keith, Sommadossi, Jean-Pierre
में प्रकाशित Open Forum Infect Dis (2020)

169. AT-752, an Oral Guanosine Nucleotide Prodrug, Exhibits Potent in Vitro Activity Against Flaviviruses and Prevents Disease Progression in a Dengue Mouse Model

द्वारा Good, Steven S, Moussa, Adel, Zhou, Xiao-Jian, Sommadossi, Jean-Pierre, Pietropaolo, Keith
में प्रकाशित Open Forum Infect Dis (2020)

Safety and Pharmacokinetics of IDX184, a Liver-Targeted Nucleotide Polymerase Inhibitor of Hepatitis C Virus, in Healthy Subjects

द्वारा Zhou, Xiao-Jian, Pietropaolo, Keith, Chen, Jie, Khan, Samina, Sullivan-Bólyai, John, Mayers, Douglas
प्रकाशित 2011

Discovery of a Series of Potent and Selective Nucleotide Prodrug Inhibitors of Respiratory Syncytial Virus (RSV) Replication

द्वारा Good, Steven, Moussa, Adel, Meillon, Jean-Cristophe, Zhou, Xiao-Jian, Pietropaolo, Keith, Sommadossi, Jean-Pierre
में प्रकाशित Open Forum Infect Dis (2017)

Single-Dose Escalation and Multiple-Dose Safety, Tolerability, and Pharmacokinetics of IDX899, a Candidate Human Immunodeficiency Virus Type 1 Nonnucleoside Reverse Transcriptase I...

द्वारा Zhou, Xiao-Jian, Pietropaolo, Keith, Damphousse, David, Belanger, Bruce, Chen, Jie, Sullivan-Bólyai, John, Mayers, Douglas
प्रकाशित 2009

Drug interaction profile for GSK2248761, a next generation non-nucleoside reverse transcriptase inhibitor

द्वारा Piscitelli, Steve, Kim, Joseph, Gould, Elizabeth, Lou, Yu, White, Scott, de Serres, Mark, Johnson, Mark, Zhou, Xiao-Jian, Pietropaolo, Keith, Mayers, Douglas
प्रकाशित 2012

Safety and Efficacy of GSK2248761, a Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor, in Treatment-Naive HIV-1-Infected Subjects

द्वारा Zala, Carlos, St. Clair, Marty, Dudas, Kathleen, Kim, Joseph, Lou, Yu, White, Scott, Piscitelli, Steve, Dumont, Etienne, Pietropaolo, Keith, Zhou, Xiao-Jian, Mayers, Douglas
प्रकाशित 2012

Safety, Pharmacokinetics, and Antiviral Activity of AT-527, a Novel Purine Nucleotide Prodrug, in Hepatitis C Virus-Infected Subjects with or without Cirrhosis

द्वारा Berliba, Elina, Bogus, Maxim, Vanhoutte, Frédéric, Berghmans, Pieter-Jan, Good, Steven S., Moussa, Adel, Pietropaolo, Keith, Murphy, Robert L., Zhou, Xiao-Jian, Sommadossi, Jean-Pierre
में प्रकाशित Antimicrob Agents Chemother (2019)

Short-Term Monotherapy with IDX184, a Liver-Targeted Nucleotide Polymerase Inhibitor, in Patients with Chronic Hepatitis C Virus Infection

द्वारा Lalezari, Jacob, Asmuth, David, Casiró, Arnaldo, Vargas, Hugo, Lawrence, Shannon, Dubuc-Patrick, Gloria, Chen, Jie, McCarville, Joseph, Pietropaolo, Keith, Zhou, Xiao-Jian, Sullivan-Bólyai, John, Mayers, Douglas
प्रकाशित 2012