Safety, Pharmacokinetics, and Antiviral Activity of AT-527, a Novel Purine Nucleotide Prodrug, in Hepatitis C Virus-Infected Subjects with or without Cirrhosis

por Berliba, Elina, Bogus, Maxim, Vanhoutte, Frédéric, Berghmans, Pieter-Jan, Good, Steven S., Moussa, Adel, Pietropaolo, Keith, Murphy, Robert L., Zhou, Xiao-Jian, Sommadossi, Jean-Pierre
Publicado en Antimicrob Agents Chemother (2019)

Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects

por McClure, Matthew W., Berliba, Elina, Tsertsvadze, Tengiz, Streinu-Cercel, Adrian, Vijgen, Leen, Astruc, Béatrice, Patat, Alain, Westland, Christopher, Chanda, Sushmita, Zhang, Qingling, Kakuda, Thomas N., Vuong, Jennifer, Khorlin, Nick, Beigelman, Leonid, Blatt, Lawrence M., Fry, John
Publicado en PLoS One (2018)