Designing and interpreting the results of first-time-to-man studies

Por Patat, Alain A.
Publicado em 2000

A safety grading scale to support dose escalation and define stopping rules for healthy subject first-entry-into-man studies: Some points to consider from the French Club Phase I*...

Por Sibille, Michel, Patat, Alain, Caplain, Henri, Donazzolo, Yves
Publicado em 2010

Pharmacodynamic interactions of a solid formulation of sodium oxybate and ethanol in healthy volunteers

Por Pross, Nathalie, Patat, Alain, Vivet, Philippe, Bidaut, Michelle, Fauchoux, Nicolas
Publicado no Br J Clin Pharmacol (2015)

Lack of pharmacokinetic interaction between retigabine and phenobarbitone at steady-state in healthy subjects

Por Ferron, Geraldine M, Patat, Alain, Parks, Virginia, Rolan, Paul, Troy, Steven M
Publicado em 2003

Safety, tolerability, pharmacokinetics and pharmacodynamics of ascending single and multiple doses of lecozotan in healthy young and elderly subjects

Por Patat, Alain, Parks, Virginia, Raje, Sangeeta, Plotka, Anna, Chassard, Didier, Coz, F Le
Publicado em 2009

Noise-induced sleep maintenance insomnia: hypnotic and residual effects of zaleplon

Por Stone, Barbara M, Turner, Claire, Mills, Sue L, Paty, Isabelle, Patat, Alain, Darwish, Mona, Danjou, Philippe
Publicado em 2002