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Discovery of a Series of Potent and Selective Nucleotide Prodrug Inhibitors of Respiratory Syncytial Virus (RSV) Replication

BACKGROUND: RSV can cause severe respiratory tract infections in infants and the elderly. Current experimental therapies include polymerase and fusion inhibitors, but their clinical use may be limited by toxicity or rapid emergence of viral resistance. Here we report new nucleotide prodrugs that are...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Open Forum Infect Dis
मुख्य लेखकों: Good, Steven, Moussa, Adel, Meillon, Jean-Cristophe, Zhou, Xiao-Jian, Pietropaolo, Keith, Sommadossi, Jean-Pierre
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631159/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1222
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