Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: Outsourcing a key task

Por Pick, Edgar
Publicado em 2014

HETEROGENEITY OF ANTIBODY-FORMING CELLS : AN ELECTRON MICROSCOPIC ANALYSIS

Por Bosman, Cesare, Feldman, Joseph D., Pick, Edgar
Publicado em 1969

Dissociation of Rac1(GDP)·RhoGDI Complexes by the Cooperative Action of Anionic Liposomes Containing Phosphatidylinositol 3,4,5-Trisphosphate, Rac Guanine Nucleotide Exchange Facto...

Por Ugolev, Yelena, Berdichevsky, Yevgeny, Weinbaum, Carolyn, Pick, Edgar
Publicado em 2008

A Prenylated p47(phox)-p67(phox)-Rac1 Chimera Is a Quintessential NADPH Oxidase Activator: MEMBRANE ASSOCIATION AND FUNCTIONAL CAPACITY

Por Mizrahi, Ariel, Berdichevsky, Yevgeny, Casey, Patrick J., Pick, Edgar
Publicado em 2010

The dehydrogenase region of the NADPH oxidase component Nox2 acts as a protein disulfide isomerase (PDI) resembling PDIA3 with a role in the binding of the activator protein p67(ph...

Por Bechor, Edna, Dahan, Iris, Fradin, Tanya, Berdichevsky, Yevgeny, Zahavi, Anat, Federman Gross, Aya, Rafalowski, Meirav, Pick, Edgar
Publicado no Front Chem (2015)

Rational design of small molecule inhibitors targeting the Rac GTPase - p67(phox) signaling axis in inflammation

Por Bosco, Emily E., Kumar, Sachin, Marchioni, Filippo, Biesiada, Jacek, Kordos, Miroslaw, Szczur, Kathleen, Meller, Jarek, Seibel, William, Mizrahi, Ariel, Pick, Edgar, Filippi, Marie-Dominique, Zheng, Yi
Publicado em 2012

Two CGD Families with a Hypomorphic Mutation in the Activation Domain of p67(phox)

Por Roos, Dirk, van Buul, Jaap D, Tool, Anton TJ, Matute, Juan D, Marchal, Christophe M, Hayee, Bu’Hussain, Köker, M Yavuz, de Boer, Martin, van Leeuwen, Karin, Segal, Anthony W, Pick, Edgar, Dinauer, Mary C
Publicado no J Clin Cell Immunol (2014)

G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction

Por Hayee, Bu'Hussain, Antonopoulos, Aristotelis, Murphy, Emma J, Rahman, Farooq Z, Sewell, Gavin, Smith, Bradley N, McCartney, Sara, Furman, Mark, Hall, Georgina, Bloom, Stuart L, Haslam, Stuart M, Morris, Howard R, Boztug, Kaan, Klein, Christoph, Winchester, Bryan, Pick, Edgar, Linch, David C, Gale, Rosemary E, Smith, Andrew M, Dell, Anne, Segal, Anthony W
Publicado em 2011