A Prenylated p47(phox)-p67(phox)-Rac1 Chimera Is a Quintessential NADPH Oxidase Activator: MEMBRANE ASSOCIATION AND FUNCTIONAL CAPACITY

The superoxide-generating NADPH oxidase complex of resting phagocytes includes cytochrome b(559), a membrane-associated heterodimer composed of two subunits (Nox2 and p22(phox)), and four cytosolic proteins (p47(phox), p67(phox), Rac, and p40(phox)). Upon stimulation, the cytosolic components transl...

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Bibliografiska uppgifter
Huvudupphovsmän: Mizrahi, Ariel, Berdichevsky, Yevgeny, Casey, Patrick J., Pick, Edgar
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919112/
https://ncbi.nlm.nih.gov/pubmed/20529851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113779
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