Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91(phox)/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67(phox), and p47(phox)

Neutrophils generate microbicidal oxidants through activation of a multicomponent enzyme called NADPH oxidase. During activation, the cytosolic NADPH oxidase components (p47(phox), p67(phox), p40(phox), and Rac2) translocate to the membranes, where they associate with flavocytochrome b(558), which i...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Raad, Houssam, Paclet, Marie-Hélène, Boussetta, Tarek, Kroviarski, Yolande, Morel, Françoise, Quinn, Mark T., Gougerot-Pocidalo, Marie-Anne, Dang, Pham My-Chan, El-Benna, Jamel
Médium: Artigo
Jazyk:Inglês
Vydáno: The Federation of American Societies for Experimental Biology 2009
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660639/
https://ncbi.nlm.nih.gov/pubmed/19028840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-114553
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky