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Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91(phox)/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67(phox), and p47(phox)
Neutrophils generate microbicidal oxidants through activation of a multicomponent enzyme called NADPH oxidase. During activation, the cytosolic NADPH oxidase components (p47(phox), p67(phox), p40(phox), and Rac2) translocate to the membranes, where they associate with flavocytochrome b(558), which i...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Federation of American Societies for Experimental Biology
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660639/ https://ncbi.nlm.nih.gov/pubmed/19028840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-114553 |
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