Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91(phox)/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67(phox), and p47(phox)

Neutrophils generate microbicidal oxidants through activation of a multicomponent enzyme called NADPH oxidase. During activation, the cytosolic NADPH oxidase components (p47(phox), p67(phox), p40(phox), and Rac2) translocate to the membranes, where they associate with flavocytochrome b(558), which i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Raad, Houssam, Paclet, Marie-Hélène, Boussetta, Tarek, Kroviarski, Yolande, Morel, Françoise, Quinn, Mark T., Gougerot-Pocidalo, Marie-Anne, Dang, Pham My-Chan, El-Benna, Jamel
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660639/
https://ncbi.nlm.nih.gov/pubmed/19028840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-114553
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados