A specific p47(phox) -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites

Neutrophil NADPH oxidase plays a key role in host defense and in inflammation by releasing large amounts of superoxide and other ROSs. Proinflammatory cytokines such as GM-CSF and TNF-α prime ROS production by neutrophils through unknown mechanisms. Here we used peptide sequencing by tandem mass spe...

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Detalhes bibliográficos
Main Authors: Dang, Pham My-Chan, Stensballe, Allan, Boussetta, Tarek, Raad, Houssam, Dewas, Cedric, Kroviarski, Yolande, Hayem, Gilles, Jensen, Ole N., Gougerot-Pocidalo, Marie-Anne, El-Benna, Jamel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479423/
https://ncbi.nlm.nih.gov/pubmed/16778989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27544
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