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Increased reactive oxygen species production and p47phox phosphorylation in neutrophils from myeloproliferative disorders patients with JAK2 (V617F) mutation

Myeloproliferative disorders are associated with increased risk of thrombosis and vascular complications. The pathogenesis of these complications is not completely known. Reactive oxygen species produced by the neutrophil NADPH oxidase could have a role in this process. The aim of this study was to...

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Main Authors: Hurtado-Nedelec, Margarita, Csillag-Grange, Marie-José, Boussetta, Tarek, Belambri, Sahra Amel, Fay, Michèle, Cassinat, Bruno, Gougerot-Pocidalo, Marie-Anne, Dang, Pham My-Chan, El-Benna, Jamel
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789455/
https://ncbi.nlm.nih.gov/pubmed/23975181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.082560
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