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Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation
A point mutation in the mouse Ncf1(m1J) gene decreases production of ROS by the phagocytic NOX2 complex. Three mRNA splice variants are expressed, but only one is expressed as a protein, although at lower levels than the WT NCF1 (also known as p47phox). Our aim was to investigate whether the mutant...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society for Leukocyte Biology
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3579024/ https://ncbi.nlm.nih.gov/pubmed/23271700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1211588 |
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