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Superoxide Dismutase 3 Limits Collagen-Induced Arthritis in the Absence of Phagocyte Oxidative Burst

Extracellular superoxide dismutase (SOD3), an enzyme mediating dismutation of superoxide into hydrogen peroxide, has been shown to reduce inflammation by inhibiting macrophage migration into injured tissues. In inflamed tissues, superoxide is produced by the phagocytic NOX2 complex, which consists o...

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Bibliografiske detaljer
Main Authors: Kelkka, Tiina, Laurila, Juha Petteri, Sareila, Outi, Olofsson, Peter, Laukkanen, Mikko Olavi, Holmdahl, Rikard
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317049/
https://ncbi.nlm.nih.gov/pubmed/22529530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/730469
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