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Superoxide Dismutase 3 Limits Collagen-Induced Arthritis in the Absence of Phagocyte Oxidative Burst

Extracellular superoxide dismutase (SOD3), an enzyme mediating dismutation of superoxide into hydrogen peroxide, has been shown to reduce inflammation by inhibiting macrophage migration into injured tissues. In inflamed tissues, superoxide is produced by the phagocytic NOX2 complex, which consists o...

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Detalhes bibliográficos
Main Authors: Kelkka, Tiina, Laurila, Juha Petteri, Sareila, Outi, Olofsson, Peter, Laukkanen, Mikko Olavi, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317049/
https://ncbi.nlm.nih.gov/pubmed/22529530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/730469
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