Superoxide Dismutase 3 Limits Collagen-Induced Arthritis in the Absence of Phagocyte Oxidative Burst

Extracellular superoxide dismutase (SOD3), an enzyme mediating dismutation of superoxide into hydrogen peroxide, has been shown to reduce inflammation by inhibiting macrophage migration into injured tissues. In inflamed tissues, superoxide is produced by the phagocytic NOX2 complex, which consists o...

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Hlavní autoři: Kelkka, Tiina, Laurila, Juha Petteri, Sareila, Outi, Olofsson, Peter, Laukkanen, Mikko Olavi, Holmdahl, Rikard
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317049/
https://ncbi.nlm.nih.gov/pubmed/22529530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/730469
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