Superoxide Dismutase 3 Limits Collagen-Induced Arthritis in the Absence of Phagocyte Oxidative Burst

Extracellular superoxide dismutase (SOD3), an enzyme mediating dismutation of superoxide into hydrogen peroxide, has been shown to reduce inflammation by inhibiting macrophage migration into injured tissues. In inflamed tissues, superoxide is produced by the phagocytic NOX2 complex, which consists o...

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Autori principali: Kelkka, Tiina, Laurila, Juha Petteri, Sareila, Outi, Olofsson, Peter, Laukkanen, Mikko Olavi, Holmdahl, Rikard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317049/
https://ncbi.nlm.nih.gov/pubmed/22529530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/730469
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