Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse immunoglobulin repertoire following immunization

Por Sundling, Christopher, Zhang, Zhenhai, Phad, Ganesh E., Sheng, Zizhang, Wang, Yimeng, Mascola, John R., Li, Yuxing, Wyatt, Richard T., Shapiro, Lawrence, Hedestam, Gunilla B. Karlsson
Publicado em 2014

Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity

Por Corcoran, Martin M., Phad, Ganesh E., Bernat, Néstor Vázquez, Stahl-Hennig, Christiane, Sumida, Noriyuki, Persson, Mats A.A., Martin, Marcel, Hedestam, Gunilla B. Karlsson
Publicado no Nat Commun (2016)

HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization

Por Navis, Marjon, Tran, Karen, Bale, Shridhar, Phad, Ganesh E., Guenaga, Javier, Wilson, Richard, Soldemo, Martina, McKee, Krisha, Sundling, Christopher, Mascola, John, Li, Yuxing, Wyatt, Richard T., Karlsson Hedestam, Gunilla B.
Publicado em 2014

Diverse antibody genetic and recognition properties revealed following HIV-1 Env immunization

Por Phad, Ganesh E., Bernat, Néstor Vázquez, Feng, Yu, Ingale, Jidnyasa, Murillo, Paola Andrea Martinez, O’Dell, Sijy, Li, Yuxing, Mascola, John R., Sundling, Christopher, Wyatt, Richard T., Karlsson Hedestam, Gunilla B.
Publicado no J Immunol (2015)

High Resolution Longitudinal Study of HIV-1 Env Vaccine-elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence

Por Wang, Yimeng, Sundling, Christopher, Wilson, Richard, O’Dell, Sijy, Chen, Yajing, Dai, Kaifan, Phad, Ganesh E., Zhu, Jiang, Xiao, Yongli, Mascola, John R., Karlsson Hedestam, Gunilla B., Wyatt, Richard T., Li, Yuxing
Publicado no J Immunol (2016)

HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation

Por Dai, Kaifan, Khan, Salar N, Wang, Yimeng, He, Linling, Guenaga, Javier, Ingale, Jidnyasa, Sundling, Christopher, O’Dell, Sijy, McKee, Krisha, Phad, Ganesh, Corcoran, Martin, Wilson, Richard, Mascola, John R, Zhu, Jiang, Li, Yuxing, Hedestam, Gunilla B Karlsson, Wyatt, Richard T
Publicado no Sci Rep (2016)

Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds

Por Madani, Navid, Princiotto, Amy M., Easterhoff, David, Bradley, Todd, Luo, Kan, Williams, Wilton B., Liao, Hua-Xin, Moody, M. Anthony, Phad, Ganesh E., Vázquez Bernat, Néstor, Melillo, Bruno, Santra, Sampa, Smith, Amos B., Karlsson Hedestam, Gunilla B., Haynes, Barton, Sodroski, Joseph
Publicado no J Virol (2016)

Particulate array of well-ordered HIV clade C Env trimers elicits neutralizing antibodies that display a unique V2 cap approach

Por Martinez-Murillo, Paola, Tran, Karen, Guenaga, Javier, Lindgren, Gustaf, Àdori, Monika, Feng, Yu, Phad, Ganesh E., Bernat, Néstor Vázquez, Bale, Shridhar, Ingale, Jidnyasa, Dubrovskaya, Viktoriya, O’Dell, Sijy, Pramanik, Lotta, Spångberg, Mats, Corcoran, Martin, Loré, Karin, Mascola, John R., Wyatt, Richard T., Karlsson Hedestam, Gunilla B.
Publicado no Immunity (2017)

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

Por Klein, Florian, Nogueira, Lilian, Nishimura, Yoshiaki, Phad, Ganesh, West, Anthony P., Halper-Stromberg, Ariel, Horwitz, Joshua A., Gazumyan, Anna, Liu, Cassie, Eisenreich, Thomas R., Lehmann, Clara, Fätkenheuer, Gerd, Williams, Constance, Shingai, Masashi, Martin, Malcolm A., Bjorkman, Pamela J., Seaman, Michael S., Zolla-Pazner, Susan, Karlsson Hedestam, Gunilla B., Nussenzweig, Michel C.
Publicado no J Exp Med (2014)