Particulate array of well-ordered HIV clade C Env trimers elicits neutralizing antibodies that display a unique V2 cap approach

The development of soluble envelope glycoprotein (Env) mimetics displaying ordered trimeric symmetry has ushered in a new era in HIV-1 vaccination. The recently reported native, flexibly linked (NFL) design allows the generation of native-like trimers from clinical isolates at high yields and homoge...

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Bibliografski detalji
Izdano u:Immunity
Glavni autori: Martinez-Murillo, Paola, Tran, Karen, Guenaga, Javier, Lindgren, Gustaf, Àdori, Monika, Feng, Yu, Phad, Ganesh E., Bernat, Néstor Vázquez, Bale, Shridhar, Ingale, Jidnyasa, Dubrovskaya, Viktoriya, O’Dell, Sijy, Pramanik, Lotta, Spångberg, Mats, Corcoran, Martin, Loré, Karin, Mascola, John R., Wyatt, Richard T., Karlsson Hedestam, Gunilla B.
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528178/
https://ncbi.nlm.nih.gov/pubmed/28514687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.04.021
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