Phosphonate Biosynthesis and Catabolism: A Treasure Trove of Unusual Enzymology

per Peck, Spencer C., van der Donk, Wilfred A.
Publicat 2013

Go It Alone: Four Electron Oxidations by Mononuclear Non-heme Iron Enzymes

per Peck, Spencer C., van der Donk, Wilfred A.
Publicat a J Biol Inorg Chem (2016)

Mechanistic Investigation of Methylphosphonate Synthase, a Non-Heme Iron-Dependent Oxygenase

per Cooke, Heather A., Peck, Spencer C., Evans, Bradley S., van der Donk, Wilfred A.
Publicat 2012

Stereochemistry of Hydride Transfer by Group III Alcohol Dehydrogenases Involved in Phosphonate Biosynthesis

per Peck, Spencer C., Kim, Seung Young, Evans, Bradley S., van der Donk, Wilfred A.
Publicat a Medchemcomm (2012)

Oxygen-18 Kinetic Isotope Effects of Nonheme Iron Enzymes HEPD and MPnS Support Iron(III) Superoxide as the Hydrogen Abstraction Species

per Zhu, Hui, Peck, Spencer C., Bonnot, Florence, van der Donk, Wilfred A., Klinman, Judith P.
Publicat a J Am Chem Soc (2015)

A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia

per Peck, Spencer C., Denger, Karin, Burrichter, Anna, Irwin, Stephania M., Balskus, Emily P., Schleheck, David
Publicat a Proc Natl Acad Sci U S A (2019)

Use of the Dehydrophos Biosynthetic Enzymes to Prepare Antimicrobial Analogs of Alaphosphin

per Bougioukou, Despina J., Ting, Chi P., Peck, Spencer C., Mukherjee, Subha, van der Donk, Wilfred A.
Publicat a Org Biomol Chem (2019)

On the Stereochemistry of 2-Hydroxyethylphosphonate Dioxygenase

per Whitteck, John T., Malova, Petra, Peck, Spencer C., Cicchillo, Robert M., Hammerschmidt, Friedrich, van der Donk, Wilfred A.
Publicat 2011

A Common Late-Stage Intermediate in Catalysis by 2-Hydroxyethyl-phosphonate Dioxygenase and Methylphosphonate Synthase

per Peck, Spencer C., Chekan, Jonathan R., Ulrich, Emily C., Nair, Satish K., van der Donk, Wilfred A.
Publicat a J Am Chem Soc (2015)

Structural basis for methylphosphonate biosynthesis

per Born, David A., Ulrich, Emily C., Ju, Kou-San, Peck, Spencer C., van der Donk, Wilfred A., Drennan, Catherine L.
Publicat a Science (2017)

Mechanism and Substrate Recognition of 2-Hydroxyethylphosphonate Dioxygenase

per Peck, Spencer C., Cooke, Heather A., Cicchillo, Robert M., Malova, Petra, Hammerschmidt, Friedrich, Nair, Satish K., van der Donk, Wilfred A.
Publicat 2011

Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation

per Agarwal, Vinayak, Peck, Spencer C., Chen, Jui-Hui, Borisova, Svetlana A., Chekan, Jonathan R., van der Donk, Wilfred A., Nair, Satish K.
Publicat a Chem Biol (2013)

Evidence that the Fosfomycin-producing Epoxidase, HppE, is a Non-heme-iron Peroxidase()

per Wang, Chen, Chang, Wei-chen, Guo, Yisong, Huang, Hui, Peck, Spencer C., Pandelia, Maria E., Lin, Geng-min, Liu, Hung-wen, Krebs, Carsten, Bollinger, J. Martin
Publicat 2013

O–H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase

per Peck, Spencer C., Wang, Chen, Dassama, Laura M. K., Zhang, Bo, Guo, Yisong, Rajakovich, Lauren J., Bollinger, J. Martin, Krebs, Carsten, van der Donk, Wilfred A.
Publicat a J Am Chem Soc (2017)