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O–H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase
[Image: see text] Activation of O–H bonds by inorganic metal-oxo complexes has been documented, but no cognate enzymatic process is known. Our mechanistic analysis of 2-hydroxyethylphosphonate dioxygenase (HEPD), which cleaves the C1–C2 bond of its substrate to afford hydroxymethylphosphonate on the...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2017
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5302023/ https://ncbi.nlm.nih.gov/pubmed/28092705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b12147 |
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