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Biosynthesis of 2-Hydroxyethylphosphonate, an Unexpected Intermediate Common to Multiple Phosphonate Biosynthetic Pathways

Phosphonic acids encompass a common yet chemically diverse class of natural products that often possess potent biological activities. Here we report that, despite the significant structural differences among many of these compounds, their biosynthetic routes contain an unexpected common intermediate...

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Hlavní autoři: Shao, Zengyi, Blodgett, Joshua A. V., Circello, Benjamin T., Eliot, Andrew C., Woodyer, Ryan, Li, Gongyong, van der Donk, Wilfred A., Metcalf, William W., Zhao, Huimin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516978/
https://ncbi.nlm.nih.gov/pubmed/18544530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801788200
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