Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis

por Phelan, James P., Lang, Simon B., Sim, Jaehoon, Berritt, Simon, Peat, Andrew J., Billings, Katelyn, Fan, Lijun, Molander, Gary A.
Publicado en J Am Chem Soc (2019)

Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, and Clinical Effect of Danirixin in Adults With Acute, Uncomplicated Influenza

por Roberts, Grace, Chen, Shuguang, Yates, Phillip, Madan, Anuradha, Walker, Jill, Washburn, Michael L, Peat, Andrew J, Soucie, Gary, Kerwin, Edward, Roy-Ghanta, Sumita
Publicado en Open Forum Infect Dis (2019)

Multi-Modal Imaging with a Toolbox of Influenza A Reporter Viruses

por Tran, Vy, Poole, Daniel S., Jeffery, Justin J., Sheahan, Timothy P., Creech, Donald, Yevtodiyenko, Aleksey, Peat, Andrew J., Francis, Kevin P., You, Shihyun, Mehle, Andrew
Publicado en Viruses (2015)

Encoded Library Technology Screening of Hepatitis C Virus NS4B Yields a Small-Molecule Compound Series with In Vitro Replicon Activity

por Arico-Muendel, Christopher, Zhu, Zhengrong, Dickson, Hamilton, Parks, Derek, Keicher, Jesse, Deng, Jianghe, Aquilani, Leah, Coppo, Frank, Graybill, Todd, Lind, Kenneth, Peat, Andrew, Thomson, Michael
Publicado en Antimicrob Agents Chemother (2015)

Efficacy and Safety of Danirixin (GSK1325756) Co-administered With Standard-of-Care Antiviral (Oseltamivir): A Phase 2b, Global, Randomized Study of Adults Hospitalized With Influe...

por Madan, Anuradha, Chen, Shuguang, Yates, Phillip, Washburn, Michael L, Roberts, Grace, Peat, Andrew J, Tao, Yu, Parry, Michael F, Barnum, Otis, McClain, Micah T, Roy-Ghanta, Sumita
Publicado en Open Forum Infect Dis (2019)

Preclinical Characterization and In Vivo Efficacy of GSK8853, a Small-Molecule Inhibitor of the Hepatitis C Virus NS4B Protein

por Pouliot, Jeffrey J., Thomson, Michael, Xie, Mi, Horton, Joseph, Johnson, John, Krull, David, Mathis, Amanda, Morikawa, Yoshio, Parks, Derek, Peterson, Richard, Shimada, Takashi, Thomas, Elizabeth, Vamathevan, Jessica, Van Horn, Stephanie, Xiong, Zhiping, Hamatake, Robert, Peat, Andrew J.
Publicado en Antimicrob Agents Chemother (2015)

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

por Briscoe, Celia P, Peat, Andrew J, McKeown, Stephen C, Corbett, David F, Goetz, Aaron S, Littleton, Thomas R, McCoy, David C, Kenakin, Terry P, Andrews, John L, Ammala, Carina, Fornwald, James A, Ignar, Diane M, Jenkinson, Stephen
Publicado 2006

Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor

por Chong, Pek Y., Shotwell, J. Brad, Miller, John, Price, Daniel J., Maynard, Andy, Voitenleitner, Christian, Mathis, Amanda, Williams, Shawn, Pouliot, Jeffrey J., Creech, Katrina, Wang, Feng, Fang, Jing, Zhang, Huichang, Tai, Vincent W.-F., Turner, Elizabeth, Kahler, Kirsten M., Crosby, Renae, Peat, Andrew J.
Publicado en J Med Chem (2019)

Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization

por Shotwell, J. Brad, Baskaran, Subramanian, Chong, Pek, Creech, Katrina L., Crosby, Renae M., Dickson, Hamilton, Fang, Jing, Garrido, Dulce, Mathis, Amanda, Maung, Jack, Parks, Derek J., Pouliot, Jeffrey J., Price, Daniel J., Rai, Roopa, Seal, John W., Schmitz, Uli, Tai, Vincent W. F., Thomson, Michael, Xie, Mi, Xiong, Zhiping Z., Peat, Andrew J.
Publicado 2012