Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, and Clinical Effect of Danirixin in Adults With Acute, Uncomplicated Influenza

BACKGROUND: Danirixin (DNX), a selective and reversible CXC chemokine receptor 2 antagonist, inhibits neutrophil transmigration and activation. This study assessed the safety, tolerability, and clinical effect of DNX with and without oseltamivir (OSV) in adults with acute, uncomplicated influenza. M...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Open Forum Infect Dis
Hauptverfasser: Roberts, Grace, Chen, Shuguang, Yates, Phillip, Madan, Anuradha, Walker, Jill, Washburn, Michael L, Peat, Andrew J, Soucie, Gary, Kerwin, Edward, Roy-Ghanta, Sumita
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Major Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476494/
https://ncbi.nlm.nih.gov/pubmed/31024969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz072
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