Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis

per Phelan, James P., Lang, Simon B., Sim, Jaehoon, Berritt, Simon, Peat, Andrew J., Billings, Katelyn, Fan, Lijun, Molander, Gary A.
Publicat a J Am Chem Soc (2019)

Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, and Clinical Effect of Danirixin in Adults With Acute, Uncomplicated Influenza

per Roberts, Grace, Chen, Shuguang, Yates, Phillip, Madan, Anuradha, Walker, Jill, Washburn, Michael L, Peat, Andrew J, Soucie, Gary, Kerwin, Edward, Roy-Ghanta, Sumita
Publicat a Open Forum Infect Dis (2019)

Multi-Modal Imaging with a Toolbox of Influenza A Reporter Viruses

per Tran, Vy, Poole, Daniel S., Jeffery, Justin J., Sheahan, Timothy P., Creech, Donald, Yevtodiyenko, Aleksey, Peat, Andrew J., Francis, Kevin P., You, Shihyun, Mehle, Andrew
Publicat a Viruses (2015)

Encoded Library Technology Screening of Hepatitis C Virus NS4B Yields a Small-Molecule Compound Series with In Vitro Replicon Activity

per Arico-Muendel, Christopher, Zhu, Zhengrong, Dickson, Hamilton, Parks, Derek, Keicher, Jesse, Deng, Jianghe, Aquilani, Leah, Coppo, Frank, Graybill, Todd, Lind, Kenneth, Peat, Andrew, Thomson, Michael
Publicat a Antimicrob Agents Chemother (2015)

Efficacy and Safety of Danirixin (GSK1325756) Co-administered With Standard-of-Care Antiviral (Oseltamivir): A Phase 2b, Global, Randomized Study of Adults Hospitalized With Influe...

per Madan, Anuradha, Chen, Shuguang, Yates, Phillip, Washburn, Michael L, Roberts, Grace, Peat, Andrew J, Tao, Yu, Parry, Michael F, Barnum, Otis, McClain, Micah T, Roy-Ghanta, Sumita
Publicat a Open Forum Infect Dis (2019)

Preclinical Characterization and In Vivo Efficacy of GSK8853, a Small-Molecule Inhibitor of the Hepatitis C Virus NS4B Protein

per Pouliot, Jeffrey J., Thomson, Michael, Xie, Mi, Horton, Joseph, Johnson, John, Krull, David, Mathis, Amanda, Morikawa, Yoshio, Parks, Derek, Peterson, Richard, Shimada, Takashi, Thomas, Elizabeth, Vamathevan, Jessica, Van Horn, Stephanie, Xiong, Zhiping, Hamatake, Robert, Peat, Andrew J.
Publicat a Antimicrob Agents Chemother (2015)

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

per Briscoe, Celia P, Peat, Andrew J, McKeown, Stephen C, Corbett, David F, Goetz, Aaron S, Littleton, Thomas R, McCoy, David C, Kenakin, Terry P, Andrews, John L, Ammala, Carina, Fornwald, James A, Ignar, Diane M, Jenkinson, Stephen
Publicat 2006

Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor

per Chong, Pek Y., Shotwell, J. Brad, Miller, John, Price, Daniel J., Maynard, Andy, Voitenleitner, Christian, Mathis, Amanda, Williams, Shawn, Pouliot, Jeffrey J., Creech, Katrina, Wang, Feng, Fang, Jing, Zhang, Huichang, Tai, Vincent W.-F., Turner, Elizabeth, Kahler, Kirsten M., Crosby, Renae, Peat, Andrew J.
Publicat a J Med Chem (2019)

Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization

per Shotwell, J. Brad, Baskaran, Subramanian, Chong, Pek, Creech, Katrina L., Crosby, Renae M., Dickson, Hamilton, Fang, Jing, Garrido, Dulce, Mathis, Amanda, Maung, Jack, Parks, Derek J., Pouliot, Jeffrey J., Price, Daniel J., Rai, Roopa, Seal, John W., Schmitz, Uli, Tai, Vincent W. F., Thomson, Michael, Xie, Mi, Xiong, Zhiping Z., Peat, Andrew J.
Publicat 2012