Establishing a Human Renal Cell Carcinoma Tumorgraft Platform for Preclinical Drug Testing

por Pavía-Jiménez, Andrea, Tcheuyap, Vanina Toffessi, Brugarolas, James
Publicado en Nat Protoc (2014)

Identification of CREB3L1 as a Biomarker Predicting Doxorubicin Treatment Outcome

por Denard, Bray, Pavia-Jimenez, Andrea, Chen, Weina, Williams, Noelle S., Naina, Harris, Collins, Robert, Brugarolas, James, Ye, Jin
Publicado en PLoS One (2015)

Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal cell carcinoma: a retrospective analysis with independent validation

por Kapur, Payal, Peña-Llopis, Samuel, Christie, Alana, Zhrebker, Leah, Pavía-Jiménez, Andrea, Rathmell, W. Kimryn, Xie, Xian-Jin, Brugarolas, James
Publicado en Lancet Oncol (2013)

High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma

por Wolff, Nicholas C., Pavía-Jiménez, Andrea, Tcheuyap, Vanina T., Alexander, Shane, Vishwanath, Mridula, Christie, Alana, Xie, Xian-Jin, Williams, Noelle S., Kapur, Payal, Posner, Bruce, McKay, Renée M., Brugarolas, James
Publicado en Oncotarget (2015)

Fibroblast Growth Factor Receptor-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant Renal Cell Carcinoma

por Tran, Tram Anh, Leong, Hon Sing, Pavia-Jimenez, Andrea, Fedyshyn, Slavic, Yang, Juan, Kucejova, Blanka, Sivanand, Sharanya, Spence, Patrick, Xie, Xian-Jin, Peña-Llopis, Samuel, Power, Nicholas, Brugarolas, James
Publicado en Mol Cell Biol (2016)

A Novel Germline Mutation in BAP1 Predisposes to Familial Clear-Cell Renal Cell Carcinoma

por Farley, Megan N., Schmidt, Laura S., Mester, Jessica L., Pena-Llopis, Samuel, Pavia-Jimenez, Andrea, Christie, Alana, Vocke, Cathy D., Ricketts, Christopher J., Peterson, James, Middelton, Lindsay, Kinch, Lisa, Grishin, Nick, Merino, Maria J., Metwalli, Adam R., Xing, Chao, Xie, Xian-Jin, Dahia, Patricia L.M., Eng, Charis, Linehan, W. Marston, Brugarolas, James
Publicado 2013

A Validated Tumorgraft Model Reveals Activity of Dovitinib Against Renal Cell Carcinoma

por Sivanand, Sharanya, Peña-Llopis, Samuel, Zhao, Hong, Kucejova, Blanka, Spence, Patrick, Pavia-Jimenez, Andrea, Yamasaki, Toshinari, McBride, David J., Gillen, Jessica, Wolff, Nicholas C., Morlock, Lorraine, Lotan, Yair, Raj, Ganesh V., Sagalowsky, Arthur, Margulis, Vitaly, Cadeddu, Jeffrey A., Ross, Mark T., Bentley, David R., Kabbani, Wareef, Xie, Xian-Jin, Kapur, Payal, Williams, Noelle S., Brugarolas, James
Publicado 2012

BAP1 loss defines a new class of renal cell carcinoma

por Peña-Llopis, Samuel, Vega-Rubín-de-Celis, Silvia, Liao, Arnold, Leng, Nan, Pavía-Jiménez, Andrea, Wang, Shanshan, Yamasaki, Toshinari, Zhrebker, Leah, Sivanand, Sharanya, Spence, Patrick, Kinch, Lisa, Hambuch, Tina, Jain, Suneer, Lotan, Yair, Margulis, Vitaly, Sagalowsky, Arthur I., Summerour, Pia Banerji, Kabbani, Wareef, Wong, S. W. Wendy, Grishin, Nick, Laurent, Marc, Xie, Xian-Jin, Haudenschild, Christian D., Ross, Mark T., Bentley, David R., Kapur, Payal, Brugarolas, James
Publicado 2012

Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI

por Zhang, Yue, Udayakumar, Durga, Cai, Ling, Hu, Zeping, Kapur, Payal, Kho, Eun-Young, Pavía-Jiménez, Andrea, Fulkerson, Michael, de Leon, Alberto Diaz, Yuan, Qing, Dimitrov, Ivan E., Yokoo, Takeshi, Ye, Jin, Mitsche, Matthew A., Kim, Hyeonwoo, McDonald, Jeffrey G., Xi, Yin, Madhuranthakam, Ananth J., Dwivedi, Durgesh K., Lenkinski, Robert E., Cadeddu, Jeffrey A., Margulis, Vitaly, Brugarolas, James, DeBerardinis, Ralph J., Pedrosa, Ivan
Publicado en JCI Insight (2017)

Targeting Renal Cell Carcinoma with a HIF-2 antagonist

por Chen, Wenfang, Hill, Haley, Christie, Alana, Kim, Min Soo, Holloman, Eboni, Pavia-Jimenez, Andrea, Homayoun, Farrah, Ma, Yuanqing, Patel, Nirav, Yell, Paul, Hao, Guiyang, Yousuf, Qurratulain, Joyce, Allison, Pedrosa, Ivan, Geiger, Heather, Zhang, He, Chang, Jenny, Gardner, Kevin H., Bruick, Richard K., Reeves, Catherine, Hwang, Tae Hyun, Courtney, Kevin, Frenkel, Eugene, Sun, Xiankai, Zojwalla, Naseem, Wong, Tai, Rizzi, James P., Wallace, Eli M., Josey, John A., Xie, Yang, Xie, Xian-Jin, Kapur, Payal, McKay, Renée M., Brugarolas, James
Publicado en Nature (2016)

Spectrum of diverse genomic alterations define non–clear cell renal carcinoma subtypes

por Durinck, Steffen, Stawiski, Eric W, Pavía-Jiménez, Andrea, Modrusan, Zora, Kapur, Payal, Jaiswal, Bijay S, Zhang, Na, Toffessi-Tcheuyap, Vanina, Nguyen, Thong T, Pahuja, Kanika Bajaj, Chen, Ying-Jiun, Saleem, Sadia, Chaudhuri, Subhra, Heldens, Sherry, Jackson, Marlena, Peña-Llopis, Samuel, Guillory, Joseph, Toy, Karen, Ha, Connie, Harris, Corissa J, Holloman, Eboni, Hill, Haley M, Stinson, Jeremy, Rivers, Celina Sanchez, Janakiraman, Vasantharajan, Wang, Weiru, Kinch, Lisa N, Grishin, Nick V, Haverty, Peter M, Chow, Bernard, Gehring, Julian S, Reeder, Jens, Pau, Gregoire, Wu, Thomas D, Margulis, Vitaly, Lotan, Yair, Sagalowsky, Arthur, Pedrosa, Ivan, de Sauvage, Frederic J, Brugarolas, James, Seshagiri, Somasekar
Publicado en Nat Genet (2014)