Fibroblast Growth Factor Receptor-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant Renal Cell Carcinoma

Antiangiogenic therapies, such as sunitinib, have revolutionized renal cell carcinoma (RCC) treatment. However, a precarious understanding of how resistance emerges and a lack of tractable experimental systems hinder progress. We evaluated the potential of primary RCC cultures (derived from tumors a...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Tran, Tram Anh, Leong, Hon Sing, Pavia-Jimenez, Andrea, Fedyshyn, Slavic, Yang, Juan, Kucejova, Blanka, Sivanand, Sharanya, Spence, Patrick, Xie, Xian-Jin, Peña-Llopis, Samuel, Power, Nicholas, Brugarolas, James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911743/
https://ncbi.nlm.nih.gov/pubmed/27141054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00189-16
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