Possible Pharmacological Approach Targeting Endoplasmic Reticulum Stress to Ameliorate Leptin Resistance in Obesity

Por Hosoi, Toru, Ozawa, Koichiro
Publicado no Front Endocrinol (Lausanne) (2016)

Insulin enhanced leptin-induced STAT3 signaling by inducing GRP78

Por Thon, Mina, Hosoi, Toru, Ozawa, Koichiro
Publicado no Sci Rep (2016)

Possible Integrative Actions of Leptin and Insulin Signaling in the Hypothalamus Targeting Energy Homeostasis

Por Thon, Mina, Hosoi, Toru, Ozawa, Koichiro
Publicado no Front Endocrinol (Lausanne) (2016)

ER stress upregulated PGE(2)/IFNγ-induced IL-6 expression and down-regulated iNOS expression in glial cells

Por Hosoi, Toru, Honda, Miya, Oba, Tatsuya, Ozawa, Koichiro
Publicado em 2013

Leptin induced GRP78 expression through the PI3K-mTOR pathway in neuronal cells

Por Thon, Mina, Hosoi, Toru, Yoshii, Michiko, Ozawa, Koichiro
Publicado no Sci Rep (2014)

Flurbiprofen Ameliorates Glucose Deprivation-Induced Leptin Resistance

Por Hosoi, Toru, Suyama, Yuka, Kayano, Takaaki, Ozawa, Koichiro
Publicado no Front Pharmacol (2016)

A unique modulator of endoplasmic reticulum stress-signalling pathways: the novel pharmacological properties of amiloride in glial cells

Por Hosoi, Toru, Kume, Ayaka, Otani, Kayo, Oba, Tatsuya, Ozawa, Koichiro
Publicado em 2010

Myeloid Differentiation Factor 88 (MyD88)-Deficiency Increases Risk of Diabetes in Mice

Por Hosoi, Toru, Yokoyama, Shota, Matsuo, Suguru, Akira, Shizuo, Ozawa, Koichiro
Publicado em 2010

Fluvoxamine Attenuated Endoplasmic Reticulum Stress-Induced Leptin Resistance

Por Hosoi, Toru, Miyahara, Tsuyoshi, Kayano, Takaaki, Yokoyama, Shota, Ozawa, Koichiro
Publicado em 2012

Inhibition of Casein Kinase 2 Modulates XBP1-GRP78 Arm of Unfolded Protein Responses in Cultured Glial Cells

Por Hosoi, Toru, Korematsu, Kenta, Horie, Naohiro, Suezawa, Takahiro, Okuma, Yasunobu, Nomura, Yasuyuki, Ozawa, Koichiro
Publicado em 2012

Key role of heat shock protein 90 in leptin‐induced STAT3 activation and feeding regulation

Por Hosoi, Toru, Kohda, Toshiko, Matsuzaki, Syu, Ishiguchi, Mizuho, Kuwamura, Ayaka, Akita, Tomoyuki, Tanaka, Junko, Ozawa, Koichiro
Publicado no Br J Pharmacol (2016)

Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress

Por Hosoi, Toru, Yamaguchi, Rie, Noji, Kikuko, Matsuo, Suguru, Baba, Sachiko, Toyoda, Keisuke, Suezawa, Takahiro, Kayano, Takaaki, Tanaka, Shinpei, Ozawa, Koichiro
Publicado em 2014

Potential Down-Regulation of Salivary Gland AQP5 by LPS via Cross-Coupling of NF-κB and p-c-Jun/c-Fos

Por Yao, Chenjuan, Purwanti, Nunuk, Karabasil, Mileva Ratko, Azlina, Ahmad, Javkhlan, Purevjav, Hasegawa, Takahiro, Akamatsu, Tetsuya, Hosoi, Toru, Ozawa, Koichiro, Hosoi, Kazuo
Publicado em 2010

TNF-α -857C>T Genotype is Predictive of Clinical Response after Treatment with Definitive 5-Fluorouracil/cisplatin-based Chemoradiotherapy in Japanese Patients with Esophageal Squa...

Por Omatsu, Hideaki, Kuwahara, Akiko, Yamamori, Motohiro, Fujita, Megumi, Okuno, Tatsuya, Miki, Ikuya, Tamura, Takao, Nishiguchi, Kohshi, Okamura, Noboru, Nakamura, Tsutomu, Azuma, Takeshi, Hirano, Takeshi, Ozawa, Koichiro, Hirai, Midori
Publicado em 2013

Endospanin1 affects oppositely body weight regulation and glucose homeostasis by differentially regulating central leptin signaling

Por Vauthier, Virginie, Roujeau, Clara, Chen, Patty, Sarkis, Chamsy, Migrenne, Stéphanie, Hosoi, Toru, Ozawa, Koichiro, Rouillé, Yves, Foretz, Marc, Mallet, Jacques, Launay, Jean-Marie, Magnan, Christophe, Jockers, Ralf, Dam, Julie
Publicado no Mol Metab (2016)