Potential Down-Regulation of Salivary Gland AQP5 by LPS via Cross-Coupling of NF-κB and p-c-Jun/c-Fos

The mRNA and protein levels of aquaporin (AQP)5 in the parotid gland were found to be potentially decreased by lipopolysaccharide (LPS) in vivo in C3H/HeN mice, but only weakly in C3H/HeJ, a TLR4 mutant mouse strain. In the LPS-injected mice, pilocarpine-stimulated saliva production was reduced by m...

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Main Authors: Yao, Chenjuan, Purwanti, Nunuk, Karabasil, Mileva Ratko, Azlina, Ahmad, Javkhlan, Purevjav, Hasegawa, Takahiro, Akamatsu, Tetsuya, Hosoi, Toru, Ozawa, Koichiro, Hosoi, Kazuo
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913374/
https://ncbi.nlm.nih.gov/pubmed/20522648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090282
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