Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress

Endoplasmic reticulum (ER) stress, caused by the accumulation of unfolded proteins, is involved in the development of obesity. We demonstrated that flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID), exhibited chaperone activity, which reduced protein aggregation and alleviated ER stress-in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hosoi, Toru, Yamaguchi, Rie, Noji, Kikuko, Matsuo, Suguru, Baba, Sachiko, Toyoda, Keisuke, Suezawa, Takahiro, Kayano, Takaaki, Tanaka, Shinpei, Ozawa, Koichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958308/
https://ncbi.nlm.nih.gov/pubmed/24421337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201303227
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge