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A unique modulator of endoplasmic reticulum stress-signalling pathways: the novel pharmacological properties of amiloride in glial cells

BACKGROUND AND PURPOSE: Stress on the endoplasmic reticulum (ER) can trigger rescuer responses such as the unfolded protein response (UPR). However, pharmacological modulators of these ER-regulated stress responses are not well understood. In the present study, we found that amiloride, a potassium-s...

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Autores principales: Hosoi, Toru, Kume, Ayaka, Otani, Kayo, Oba, Tatsuya, Ozawa, Koichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825364/
https://ncbi.nlm.nih.gov/pubmed/20015086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00544.x
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