Macromolecular assembly of polycystin-2 intracytosolic C-terminal domain

Por Ferreira, Frederico M., Oliveira, Leandro C., Germino, Gregory G., Onuchic, José N., Onuchic, Luiz F.
Publicado em 2011

Immunohistochemical detection of polyductin and co-localization with liver progenitor cell markers during normal and abnormal development of the intrahepatic biliary system and in...

Por Dorn, Livia, Menezes, Luís F, Mikuz, Gregor, Otto, Herwart F, Onuchic, Luiz F, Sergi, Consolato
Publicado no J Cell Mol Med (2009)

Biliary and Pancreatic Dysgenesis in Mice Harboring a Mutation in Pkhd1

Por Gallagher, Anna-Rachel, Esquivel, Ernie L., Briere, Tiffany S., Tian, Xin, Mitobe, Michihiro, Menezes, Luis F., Markowitz, Glen S., Jain, Dhanpat, Onuchic, Luiz F., Somlo, Stefan
Publicado em 2008

Pkd1 Haploinsufficiency Increases Renal Damage and Induces Microcyst Formation following Ischemia/Reperfusion

Por Bastos, Ana P., Piontek, Klaus, Silva, Ana M., Martini, Dino, Menezes, Luis F., Fonseca, Jonathan M., Fonseca, Ivone I., Germino, Gregory G., Onuchic, Luiz F.
Publicado em 2009

Dialysis as a Treatment Option for a Patient With Normal Kidney Function and Familial Tumoral Calcinosis Due to a Compound Heterozygous FGF23 Mutation

Por Goldenstein, Patrícia T., Neves, Precil D., Balbo, Bruno E., Elias, Rosilene M., Pereira, Alexandre C., Onuchic, Luiz F., Jüppner, Harald, Jorgetti, Vanda, Abensur, Hugo, Moysés, Rosa Maria
Publicado no Am J Kidney Dis (2018)

Genetic Interaction Studies Link Autosomal Dominant And Recessive Polycystic Kidney Disease In A Common Pathway

Por Garcia-Gonzalez, Miguel A., Menezes, Luis F., Piontek, Klaus B., Kaimori, Junya, Huso, David L., Watnick, Terry, Onuchic, Luiz F., Guay-Woodford, Lisa M., Germino, Gregory G.
Publicado em 2007

Renal cyst growth is the main determinant for hypertension and concentrating deficit in PKD1-deficient mice

Por Fonseca, Jonathan M., Bastos, Ana P., Amaral, Andressa G., Sousa, Mauri F., Souza, Leandro E., Malheiros, Denise M., Piontek, Klaus, Irigoyen, Maria C., Watnick, Terry J., Onuchic, Luiz F.
Publicado no Kidney Int (2014)

Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1

Por Boddu, Ravindra, Yang, Chaozhe, O’Connor, Amber K., Hendrickson, Robert Curtis, Boone, Braden, Cui, Xiangqin, Garcia-Gonzalez, Miguel, Igarashi, Peter, Onuchic, Luiz F., Germino, Gregory G., Guay-Woodford, Lisa M.
Publicado em 2014

Cardiac dysfunction in Pkd1-deficient mice with phenotype rescue by galectin-3 knockout

Por Balbo, Bruno E., Amaral, Andressa G., Fonseca, Jonathan M., de Castro, Isac, Salemi, Vera M., Souza, Leandro E., dos Santos, Fernando, Irigoyen, Maria C., Qian, Feng, Chammas, Roger, Onuchic, Luiz F.
Publicado no Kidney Int (2016)

PKHD1, the Polycystic Kidney and Hepatic Disease 1 Gene, Encodes a Novel Large Protein Containing Multiple Immunoglobulin-Like Plexin-Transcription–Factor Domains and Parallel Beta...

Por Onuchic, Luiz F., Furu, Laszlo, Nagasawa, Yasuyuki, Hou, Xiaoying, Eggermann, Thomas, Ren, Zhiyong, Bergmann, Carsten, Senderek, Jan, Esquivel, Ernie, Zeltner, Raoul, Rudnik-Schöneborn, Sabine, Mrug, Michael, Sweeney, William, Avner, Ellis D., Zerres, Klaus, Guay-Woodford, Lisa M., Somlo, Stefan, Germino, Gregory G.
Publicado em 2002

NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology

Por Kaimori, Jun-ya, Lin, Cheng-Chao, Outeda, Patricia, Garcia-Gonzalez, Miguel A., Menezes, Luis F., Hartung, Erum A., Li, Ao, Wu, Guanqing, Fujita, Hideaki, Sato, Yasunori, Nakanuma, Yasuni, Yamamoto, Satoko, Ichimaru, Naotsugu, Takahara, Shiro, Isaka, Yoshitaka, Watnick, Terry, Onuchic, Luiz F., Guay-Woodford, Lisa M., Germino, Gregory G.
Publicado no Sci Rep (2017)

Polycystin: In vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein

Por Ibraghimov-Beskrovnaya, Oxana, Dackowski, William R., Foggensteiner, Lukas, Coleman, Nick, Thiru, Sathia, Petry, Linda R., Burn, Timothy C., Connors, Timothy D., Van Raay, Terence, Bradley, John, Qian, Feng, Onuchic, Luiz F., Watnick, Terry J., Piontek, Klaus, Hakim, Raymond M., Landes, Gregory M., Germino, Gregory G., Sandford, Richard, Klinger, Katherine W.
Publicado em 1997