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Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1

Autosomal recessive polycystic kidney disease (ARPKD) results from mutations in the human PKHD1 gene. Both this gene, and its mouse ortholog, Pkhd1, are primarily expressed in renal and biliary ductal structures. The mouse protein product, fibrocystin/polyductin complex (FPC), is a 445-kDa protein e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Boddu, Ravindra, Yang, Chaozhe, O’Connor, Amber K., Hendrickson, Robert Curtis, Boone, Braden, Cui, Xiangqin, Garcia-Gonzalez, Miguel, Igarashi, Peter, Onuchic, Luiz F., Germino, Gregory G., Guay-Woodford, Lisa M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197071/
https://ncbi.nlm.nih.gov/pubmed/24984783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1185-7
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