PARI overexpression promotes genomic instability and pancreatic tumorigenesis

Por O’Connor, Kevin W., Dejsuphong, Donniphat, Park, Eunmi, Nicolae, Claudia M., Kimmelman, Alec C., D’Andrea, Alan D., Moldovan, George-Lucian
Publicado em 2013

A Unique Subset of Epithelial Ovarian Cancers with Platinum Sensitivity and PARP Inhibitor Resistance

Por Ceccaldi, Raphael, O'Connor, Kevin W., Mouw, Kent W., Li, Adam Y., Matulonis, Ursula A., D'Andrea, Alan D., Konstantinopoulos, Panagiotis A.
Publicado no Cancer Res (2015)

Homologous recombination-deficient tumors are hyper-dependent on POLQ-mediated repair

Por Ceccaldi, Raphael, Liu, Jessica C., Amunugama, Ravindra, Hajdu, Ildiko, Primack, Benjamin, Petalcorin, Mark I.R., O'Connor, Kevin W., Konstantinopoulos, Panagiotis A., Elledge, Stephen J., Boulton, Simon J., Yusufzai, Timur, D'Andrea, Alan D.
Publicado no Nature (2015)

TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia

Por Zhang, Haojian, Kozono, David E, O’Connor, Kevin W, Vidal-Cardenas, Sofia, Rousseau, Alix, Hamilton, Abigail, Moreau, Lisa, Gaudiano, Emily F, Greenberger, Joel, Bagby, Grover, Soulier, Jean, Grompe, Markus, Parmar, Kalindi, D’Andrea, Alan D
Publicado no Cell Stem Cell (2016)

Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma

Por Van Allen, Eliezer M., Mouw, Kent W., Kim, Philip, Iyer, Gopa, Wagle, Nikhil, Al-Ahmadie, Hikmat, Zhu, Cong, Ostrovnaya, Irina, Kryukov, Gregory V., O’Connor, Kevin W, Sfakianos, John, Garcia-Grossman, Ilana, Kim, Jaegil, Guancial, Elizabeth A., Bambury, Richard, Bahl, Samira, Gupta, Namrata, Farlow, Deborah, Qu, Angela, Signoretti, Sabina, Barletta, Justine A., Reuter, Victor, Boehm, Jesse, Lawrence, Michael, Getz, Gad, Kantoff, Philip, Bochner, Bernard H., Choueiri, Toni K., Bajorin, Dean F., Solit, David B., Gabriel, Stacey, D’Andrea, Alan, Garraway, Levi A., Rosenberg, Jonathan E.
Publicado no Cancer Discov (2014)