Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation

Por Michielsen, Adriana J., O’Sullivan, Jacintha N., Ryan, Elizabeth J.
Publicado em 2012

Dendritic cell inhibition correlates with survival of colorectal cancer patients on bevacizumab treatment

Por Michielsen, Adriana J., Ryan, Elizabeth J., O’Sullivan, Jacintha N.
Publicado em 2012

THE EFFECT OF GREEN TEA ON OXIDATIVE DAMAGE AND TUMOUR FORMATION IN LOBUND-WISTAR RATS

Por O'Sullivan, Jacintha, Sheridan, Juliette, Mulcahy, Hugh, Tenniswood, Martin, Morrissey, Colm
Publicado em 2008

Current targeted therapies in the treatment of advanced colorectal cancer: a review

Por Moriarity, Andrew, O’Sullivan, Jacintha, Kennedy, John, Mehigan, Brian, McCormick, Paul
Publicado no Ther Adv Med Oncol (2016)

Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer

Por Burke, Lorraine, Butler, Clare T., Murphy, Adrian, Moran, Bruce, Gallagher, William M., O'Sullivan, Jacintha, Kennedy, Breandán N.
Publicado no Front Cell Dev Biol (2016)

Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer

Por Ericson, Nolan G., Kulawiec, Mariola, Vermulst, Marc, Sheahan, Kieran, O'Sullivan, Jacintha, Salk, Jesse J., Bielas, Jason H.
Publicado em 2012

Altered Mitochondrial Function and Energy Metabolism Is Associated with a Radioresistant Phenotype in Oesophageal Adenocarcinoma

Por Lynam-Lennon, Niamh, Maher, Stephen G., Maguire, Aoife, Phelan, James, Muldoon, Cian, Reynolds, John V., O’Sullivan, Jacintha
Publicado em 2014

A Quininib Analogue and Cysteinyl Leukotriene Receptor Antagonist Inhibits Vascular Endothelial Growth Factor (VEGF)-independent Angiogenesis and Exerts an Additive Antiangiogenic...

Por Butler, Clare T., Reynolds, Alison L., Tosetto, Miriam, Dillon, Eugene T., Guiry, Patrick J., Cagney, Gerard, O'Sullivan, Jacintha, Kennedy, Breandán N.
Publicado no J Biol Chem (2017)

A prospective investigation of predictive and modifiable risk factors for breast cancer in unaffected BRCA1 and BRCA2 gene carriers

Por Guinan, Emer M, Hussey, Juliette, McGarrigle, Sarah A, Healy, Laura A, O’Sullivan, Jacintha N, Bennett, Kathleen, Connolly, Elizabeth M
Publicado em 2013

Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

Por Biniecka, Monika, Kennedy, Aisling, Ng, Chin T, Chang, Ting C, Balogh, Emese, Fox, Edward, Veale, Douglas J, Fearon, Ursula, O'Sullivan, Jacintha N
Publicado em 2011

Heterogeneity of tumor-induced gene expression changes in the human metabolic network

Por Hu, Jie, Locasale, Jason W., Bielas, Jason H., O’Sullivan, Jacintha, Sheahan, Kieran, Cantley, Lewis C., Vander Heiden, Matthew G., Vitkup, Dennis
Publicado em 2013

Genomic Biomarkers to Improve Ulcerative Colitis Neoplasia Surveillance

Por Bronner, Mary P., O'Sullivan, Jacintha N., Rabinovitch, Peter S., Crispin, David A., Chen, Lu, Emond, Mary J., Rubin, Cyrus E., Brentnall, Teresa A.
Publicado em 2008

Low MiR-187 Expression Promotes Resistance to Chemoradiation Therapy In Vitro and Correlates with Treatment Failure in Patients with Esophageal Adenocarcinoma

Por Lynam-Lennon, Niamh, Bibby, Becky A S, Mongan, Ann Marie, Marignol, Laure, Paxton, Christian N, Geiersbach, Katherine, Bronner, Mary P, O’Sullivan, Jacintha, Reynolds, John V, Maher, Stephen G
Publicado no Mol Med (2016)

Predicting response to vascular endothelial growth factor inhibitor and chemotherapy in metastatic colorectal cancer

Por Martin, Petra, Noonan, Sinead, Mullen, Michael P, Scaife, Caitriona, Tosetto, Miriam, Nolan, Blathnaid, Wynne, Kieran, Hyland, John, Sheahan, Kieran, Elia, Giuliano, O’Donoghue, Diarmuid, Fennelly, David, O’Sullivan, Jacintha
Publicado no BMC Cancer (2014)

Expression of protein kinase C gamma promotes cell migration in colon cancer

Por Dowling, Catríona M., Hayes, Sheri L., Phelan, James J., Cathcart, Mary Clare, Finn, Stephen P., Mehigan, Brian, McCormick, Paul, Coffey, John C., O'sullivan, Jacintha, Kiely, Patrick A.
Publicado no Oncotarget (2017)

Excess visceral adiposity induces alterations in mitochondrial function and energy metabolism in esophageal adenocarcinoma

Por Lynam-Lennon, Niamh, Connaughton, Ruth, Carr, Eibhlin, Mongan, Ann-Marie, O’Farrell, Naoimh J, Porter, Richard K, Brennan, Lorraine, Pidgeon, Graham P, Lysaght, Joanne, Reynolds, John V, O’Sullivan, Jacintha
Publicado no BMC Cancer (2014)

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival

Por Dowling, Catríona M., Phelan, James, Callender, Julia A., Cathcart, Mary Clare, Mehigan, Brian, McCormick, Paul, Dalton, Tara, Coffey, John C., Newton, Alexandra C., O'sullivan, Jacintha, Kiely, Patrick A.
Publicado no Oncotarget (2016)

Tumour Tissue Microenvironment Can Inhibit Dendritic Cell Maturation in Colorectal Cancer

Por Michielsen, Adriana J., Hogan, Andrew E., Marry, Joseph, Tosetto, Miriam, Cox, Fionnuala, Hyland, John M., Sheahan, Kieran D., O'Donoghue, Diarmuid P., Mulcahy, Hugh E., Ryan, Elizabeth J., O'Sullivan, Jacintha N.
Publicado em 2011

Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a(-/- )mutants

Por Sapetto-Rebow, Beata, McLoughlin, Sarah C, O'Shea, Lynne C, O'Leary, Olivia, Willer, Jason R, Alvarez, Yolanda, Collery, Ross, O'Sullivan, Jacintha, Van Eeden, Freek, Hensey, Carmel, Kennedy, Breandán N
Publicado em 2011

Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer

Por Murphy, Adrian G., Casey, Rory, Maguire, Aoife, Tosetto, Miriam, Butler, Clare T., Conroy, Emer, Reynolds, Alison L., Sheahan, Kieran, O’Donoghue, Diarmuid, Gallagher, William M., Fennelly, David, Kennedy, Breandán N., O’Sullivan, Jacintha
Publicado no Sci Rep (2016)