Antibiotic discovery is a walk in the park

por Nothias, Louis-Félix, Knight, Rob, Dorrestein, Pieter C.
Publicado no Proc Natl Acad Sci U S A (2016)

Specialized Metabolites from Ribosome Engineered Strains of Streptomyces clavuligerus

por Shaikh, Arshad Ali, Nothias, Louis-Felix, Srivastava, Santosh K., Dorrestein, Pieter C., Tahlan, Kapil
Publicado no Metabolites (2021)

Genomic and Metabolomic Analysis of the Potato Common Scab Pathogen Streptomyces scabiei

por Liu, Jingyu, Nothias, Louis-Félix, Dorrestein, Pieter C., Tahlan, Kapil, Bignell, Dawn R. D.
Publicado no ACS Omega (2021)

Metabolites from Microbes Isolated from the Skin of the Panamanian Rocket Frog Colostethus panamansis (Anura: Dendrobatidae)

por Martin H., Christian, Ibáñez, Roberto, Nothias, Louis-Félix, Caraballo-Rodríguez, Andrés Mauricio, Dorrestein, Pieter C., Gutiérrez, Marcelino
Publicado no Metabolites (2020)

Significance estimation for large scale metabolomics annotations by spectral matching

por Scheubert, Kerstin, Hufsky, Franziska, Petras, Daniel, Wang, Mingxun, Nothias, Louis-Félix, Dührkop, Kai, Bandeira, Nuno, Dorrestein, Pieter C., Böcker, Sebastian
Publicado no Nat Commun (2017)

Dereplication of peptidic natural products through database search of mass spectra

por Mohimani, Hosein, Gurevich, Alexey, Mikheenko, Alla, Garg, Neha, Nothias, Louis-Felix, Ninomiya, Akihiro, Takada, Kentaro, Dorrestein, Pieter C., Pevzner, Pavel A.
Publicado no Nat Chem Biol (2016)

Identification of four amoebicidal non-toxic compounds by a molecular docking screen of Naegleria fowleri sterol Δ8−Δ7-isomerase and phenotypic assays

por Shi, Da, Chahal, Kirti Kandhwal, Oto, Patricia, Nothias, Louis-Felix, Debnath, Anjan, McKerrow, James H., Podust, Larissa M., Abagyan, Ruben
Publicado no ACS Infect Dis (2019)

Dereplication of microbial metabolites through database search of mass spectra

por Mohimani, Hosein, Gurevich, Alexey, Shlemov, Alexander, Mikheenko, Alla, Korobeynikov, Anton, Cao, Liu, Shcherbin, Egor, Nothias, Louis-Felix, Dorrestein, Pieter C., Pevzner, Pavel A.
Publicado no Nat Commun (2018)

Viscosin-like lipopeptides from frog skin bacteria inhibit Aspergillus fumigatus and Batrachochytrium dendrobatidis detected by imaging mass spectrometry and molecular networking

por Martin H., Christian, Ibáñez, Roberto, Nothias, Louis-Félix, Boya P., Cristopher A., Reinert, Laura K., Rollins-Smith, Louise A., Dorrestein, Pieter C., Gutiérrez, Marcelino
Publicado no Sci Rep (2019)

Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism

por AbuSara, Nader F., Piercey, Brandon M., Moore, Marcus A., Shaikh, Arshad Ali, Nothias, Louis-Félix, Srivastava, Santosh K., Cruz-Morales, Pablo, Dorrestein, Pieter C., Barona-Gómez, Francisco, Tahlan, Kapil
Publicado no Front Microbiol (2019)

MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools

por Ernst, Madeleine, Kang, Kyo Bin, Caraballo-Rodríguez, Andrés Mauricio, Nothias, Louis-Felix, Wandy, Joe, Chen, Christopher, Wang, Mingxun, Rogers, Simon, Medema, Marnix H., Dorrestein, Pieter C., van der Hooft, Justin J.J.
Publicado no Metabolites (2019)

Propagating annotations of molecular networks using in silico fragmentation

por da Silva, Ricardo R., Wang, Mingxun, Nothias, Louis-Félix, van der Hooft, Justin J. J., Caraballo-Rodríguez, Andrés Mauricio, Fox, Evan, Balunas, Marcy J., Klassen, Jonathan L., Lopes, Norberto Peporine, Dorrestein, Pieter C.
Publicado no PLoS Comput Biol (2018)

Niche partitioning of a pathogenic microbiome driven by chemical gradients

por Quinn, Robert A., Comstock, William, Zhang, Tianyu, Morton, James T., da Silva, Ricardo, Tran, Alda, Aksenov, Alexander, Nothias, Louis-Felix, Wangpraseurt, Daniel, Melnik, Alexey V., Ackermann, Gail, Conrad, Douglas, Klapper, Isaac, Knight, Rob, Dorrestein, Pieter C.
Publicado no Sci Adv (2018)

Before platelets: the production of platelet-activating factor during growth and stress in a basal marine organism

por Galtier d'Auriac, Ines, Quinn, Robert A., Maughan, Heather, Nothias, Louis-Felix, Little, Mark, Kapono, Clifford A., Cobian, Ana, Reyes, Brandon T., Green, Kevin, Quistad, Steven D., Leray, Matthieu, Smith, Jennifer E., Dorrestein, Pieter C., Rohwer, Forest, Deheyn, Dimitri D., Hartmann, Aaron C.
Publicado no Proc Biol Sci (2018)

Assessing Specialized Metabolite Diversity in the Cosmopolitan Plant Genus Euphorbia L.

por Ernst, Madeleine, Nothias, Louis-Félix, van der Hooft, Justin J. J., Silva, Ricardo R., Saslis-Lagoudakis, C. Haris, Grace, Olwen M., Martinez-Swatson, Karen, Hassemer, Gustavo, Funez, Luís A., Simonsen, Henrik T., Medema, Marnix H., Staerk, Dan, Nilsson, Niclas, Lovato, Paola, Dorrestein, Pieter C., Rønsted, Nina
Publicado no Front Plant Sci (2019)

A Convolutional Neural Network-based approach for the Rapid Annotation of Molecularly Diverse Natural Products

por Reher, Raphael, Kim, Hyun Woo, Zhang, Chen, Mao, Huanru Henry, Wang, Mingxun, Nothias, Louis-Félix, Caraballo-Rodriguez, Andres Mauricio, Glukhov, Evgenia, Teke, Bahar, Leao, Tiago, Alexander, Kelsey L., Duggan, Brendan M., Van Everbroeck, Ezra L., Dorrestein, Pieter C., Cottrell, Garrison W., Gerwick, William H.
Publicado no J Am Chem Soc (2020)

Learning accurate representations of microbe-metabolite interactions

por Morton, James T., Aksenov, Alexander A., Nothias, Louis Felix, Foulds, James R., Quinn, Robert A., Badri, Michelle H., Swenson, Tami L., Van Goethem, Marc W., Northen, Trent R., Vazquez-Baeza, Yoshiki, Wang, Mingxun, Bokulich, Nicholas A., Watters, Aaron, Song, Se Jin, Bonneau, Richard, Dorrestein, Pieter C., Knight, Rob
Publicado no Nat Methods (2019)

Chemically informed analyses of metabolomics mass spectrometry data with Qemistree

por Tripathi, Anupriya, Vázquez-Baeza, Yoshiki, Gauglitz, Julia M., Wang, Mingxun, Dührkop, Kai, Nothias-Esposito, Mélissa, Acharya, Deepa D., Ernst, Madeleine, van der Hooft, Justin J.J., Zhu, Qiyun, McDonald, Daniel, Brejnrod, Asker D., Gonzalez, Antonio, Handelsman, Jo, Fleischauer, Markus, Ludwig, Marcus, Böcker, Sebastian, Nothias, Louis-Félix, Knight, Rob, Dorrestein, Pieter C.
Publicado no Nat Chem Biol (2020)

MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities

por Cao, Liu, Gurevich, Alexey, Alexander, Kelsey L., Naman, C. Benjamin, Leão, Tiago, Glukhov, Evgenia, Luzzatto-Knaan, Tal, Vargas, Fernando, Quinn, Robby, Bouslimani, Amina, Nothias, Louis Felix, Singh, Nitin K., Sanders, Jon G., Benitez, Rodolfo A. S., Thompson, Luke R., Hamid, Md-Nafiz, Morton, James T., Mikheenko, Alla, Shlemov, Alexander, Korobeynikov, Anton, Friedberg, Iddo, Knight, Rob, Venkateswaran, Kasthuri, Gerwick, William H., Gerwick, Lena, Dorrestein, Pieter C., Pevzner, Pavel A., Mohimani, Hosein
Publicado no Cell Syst (2019)

Mass Spectrometry-Based 3D Cartography Displays the Chemistry Associated with Modern Human Habitats

por Petras, Daniel, Nothias, Louis-Félix, Quinn, Robert A., Alexandrov, Theodore, Bandeira, Nuno, Bouslimani, Amina, Castro-Falcón, Gabriel, Chen, Liangyu, Dang, Tam, Floros, Dimitrios J, Hook, Vivian, Garg, Neha, Hoffner, Nicole, Jiang, Yike, Kapono, Clifford A., Koester, Irina, Knight, Rob, Leber, Christopher A, Ling, Tie-Jun, Luzzatto-Knaan, Tal, McCall, Laura-Isobel, McGrath, Aaron P., Meehan, Michael J., Merritt, Jonathan K., Mills, Robert H., Morton, Jamie, Podvin, Sonia, Protsyuk, Ivan, Purdy, Trevor, Satterfield, Kendall, Searles, Stephen, Shah, Sahil, Shires, Sarah, Steffen, Dana, White, Margot, Todoric, Jelena, Tuttle, Robert, Wojnicz, Aneta, Sapp, Valerie, Vargas, Fernando, Yang, Jin, Zhang, Chao, Dorrestein, Pieter C.
Publicado no Anal Chem (2016)